胸外科住院肺癌合并慢性阻塞性肺疾病的调查结果分析
发布时间：2018-10-14 10:08
【摘要】：背景与目的肺癌是慢性阻塞性肺疾病(慢阻肺)重要的合并症,会显著影响慢阻肺患者的预后。慢阻肺也会影响肺癌患者的术后并发症和复发。本研究旨在调查胸外科住院肺癌合并慢阻肺的情况。方法回顾性分析北京大学人民医院胸外科2015年1月-2015年12月收治的原发性非小细胞肺癌患者。通过查阅病历获取患者的性别、年龄、吸烟状况、有害职业史、症状、胸部计算机断层扫描(computed tomography,CT)、术后病理、出院诊断、全套肺功能及支气管舒张试验,当基础肺功能第一秒钟用力呼气容积(forced expiratory volume in one second,FEV_1)占预计值70%时即行支气管舒张试验。结果 703例肺癌患者进行了全套肺功能测定,其中67例进行支气管舒张试验,62例(92.5%)符合慢阻肺诊断。接受手术治疗的肺癌患者有677例,其中41例进行支气管舒张试验,38例(92.7%)符合慢阻肺诊断。在接受手术治疗的肺癌患者中合并慢阻肺者年龄≥65岁、男性、有吸烟史和非腺癌的比例高于未合并慢阻肺者,差异有统计学意义(P0.05);男性和≥65岁者更易合并慢阻肺(OR:2.807-2.374,95%CI:1.101-7.157)(P0.05)。住院前仅有3例(4.3‰)诊断慢阻肺并按慢阻肺规范治疗。出院时仅有5例(7.1‰)诊断慢阻肺。结论在胸外科住院肺癌患者中行常规肺功能及支气管舒张试验可提高肺癌合并慢阻肺的诊断;当前肺癌合并慢阻肺诊断和治疗严重不足,需要引起胸外科医生重视,与呼吸内科医生携手共同防治慢阻肺。
[Abstract]:Background & objective Lung cancer is an important complication of chronic obstructive pulmonary disease (COPD). COPD also affects postoperative complications and recurrence in patients with lung cancer. The purpose of this study was to investigate the lung cancer complicated with COPD in thoracic surgery. Methods the patients with primary non-small cell lung cancer admitted from January 2015 to December 2015 in the Department of Thoracic surgery in people's Hospital of Peking University were retrospectively analyzed. The patient's sex, age, smoking status, harmful occupational history, symptoms, chest computed tomography (computed tomography,CT), postoperative pathology, discharge diagnosis, complete lung function and bronchodiastolic test were obtained by consulting the medical records. Bronchodiastolic test was performed when the first second forced expiratory volume (forced expiratory volume in one second,FEV_1) of the underlying lung function was 70% of the predicted value. Results 703 patients with lung cancer underwent a complete set of pulmonary function tests, of which 67 cases were performed bronchodiastolic test, 62 cases (92.5%) were in accordance with the diagnosis of COPD. There were 677 cases of lung cancer treated surgically, of which 41 cases were treated with bronchodilation test. 38 cases (92.7%) were diagnosed as chronic obstructive pulmonary disease. In patients with lung cancer treated by surgery, the age of patients with COPD was more than 65 years old, male, smoking history and non-adenocarcinoma were higher than those without COPD (P0.05); males and 鈮，
本文编号：2270137
[Abstract]:Background & objective Lung cancer is an important complication of chronic obstructive pulmonary disease (COPD). COPD also affects postoperative complications and recurrence in patients with lung cancer. The purpose of this study was to investigate the lung cancer complicated with COPD in thoracic surgery. Methods the patients with primary non-small cell lung cancer admitted from January 2015 to December 2015 in the Department of Thoracic surgery in people's Hospital of Peking University were retrospectively analyzed. The patient's sex, age, smoking status, harmful occupational history, symptoms, chest computed tomography (computed tomography,CT), postoperative pathology, discharge diagnosis, complete lung function and bronchodiastolic test were obtained by consulting the medical records. Bronchodiastolic test was performed when the first second forced expiratory volume (forced expiratory volume in one second,FEV_1) of the underlying lung function was 70% of the predicted value. Results 703 patients with lung cancer underwent a complete set of pulmonary function tests, of which 67 cases were performed bronchodiastolic test, 62 cases (92.5%) were in accordance with the diagnosis of COPD. There were 677 cases of lung cancer treated surgically, of which 41 cases were treated with bronchodilation test. 38 cases (92.7%) were diagnosed as chronic obstructive pulmonary disease. In patients with lung cancer treated by surgery, the age of patients with COPD was more than 65 years old, male, smoking history and non-adenocarcinoma were higher than those without COPD (P0.05); males and 鈮，
本文编号：2270137
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