肺咳停合剂联合阿斯美治疗风邪伏肺型感染后咳嗽的临床疗效观察
发布时间：2018-10-17 10:22
【摘要】：目的:观察肺咳停合剂联合阿斯美治疗风邪伏肺型感染后咳嗽患者的临床疗效,探讨其作用机制,为中西医结合治疗风邪伏肺型感染后咳嗽提供一定的临床依据。方法:选取2015年1月至2016年12月武汉市第一医院呼吸内科门诊就诊的120例风邪伏肺型感染后咳嗽患者作为研究对象。这些患者随机分为西药组、中药组、中西药联合组。西药组给予阿斯美(复方甲氧那明)治疗,中药组给予肺咳停合剂治疗,中西药联合组给予肺咳停合剂和阿斯美(复方甲氧那明)治疗,疗程共10天,治疗10天后观察患者临床疗效,中医单项症状积分变化以及中医证候总积分变化,并对其安全性进行评价。运用统计学软件分析这些临床观察指标的统计学差异,比较阿斯美、肺咳停合剂、以及两药联合在治疗风邪伏肺型感染后咳嗽的有效率及三者在治疗咳嗽、咳痰、咽痒等方面的治疗效果。结果:(1)临床疗效:西药组治疗后总有效率为68.4%,中药组治疗后总有效率为61.5%,中西药联合组治疗后总有效率为83.8%,统计学分析,三组治疗后总有效率差异有统计学意义(P0.05),中西药联合组疗效显著。(2)治疗后中医单项症状积分:三组治疗后咳嗽、咳痰、咽痒症状积分均较治疗前减少,具有统计学意义(P0.05);咳嗽症状积分减少顺序为:中西药联合组西药组中药组,组间差异具有统计学意义(P0.05);咳痰症状积分减少顺序为:中西药联合组中药组西药组,组间差异具有统计学意义(P0.05);咽痒症状积分减少顺序,中西药联合组中药组西药组,组间差异具有统计学意义(P0.05)。(3)治疗后中医证候总积分:三组治疗后中医证候总积分较治疗前差异有统计学意义(P0.05);中西药联合组中医证候总积分减少更为明显,中药组和西药组中医证候总积分差异无统计学意义(P0.05)。结论:肺咳停合剂、阿斯美能够改善风邪伏肺型感染后咳嗽患者的临床症状,两药联合治疗能更有效的缓解咳嗽咳痰症状,提高临床疗效。在临床疗效方面,肺咳停合剂与阿斯美疗效相当。肺咳停合剂联合阿斯美能明显缓解患者咳嗽、咳痰、咽痒等症状,治疗风邪伏肺型感染后咳嗽有较显著的疗效。
[Abstract]:Objective: to observe the clinical effect of Feiketing mixture (FKT) combined with Asmet in treating cough after wind-pathogenic lung infection, and to explore its mechanism, and to provide some clinical basis for the treatment of wind-pathogenic pulmonary infection with combined TCM and western medicine. Methods: from January 2015 to December 2016, 120 patients with cough after wind-induced pulmonary infection in Department of Respiratory Medicine, the first Hospital of Wuhan, were selected as study objects. These patients were randomly divided into western medicine group and combined Chinese and western medicine group. The western medicine group was treated with Asmectin (compound methoxifen), the traditional Chinese medicine group was treated with the Feiketan mixture, and the Chinese and western medicine combination group was treated with the combination of the Chinese medicine and the western medicine. The course of treatment was 10 days. After 10 days of treatment, the clinical efficacy, the change of TCM single symptom integral and the total score of TCM syndromes were observed, and the safety was evaluated. Statistical software was used to analyze the statistical differences of these clinical observation indexes, to compare the effective rate of Asmat, Feiketing mixture, and the combination of the two drugs in the treatment of lung type infection caused by wind evil, and to treat cough, expectoration and phlegm among the three groups. The therapeutic effect of pharynx itching and other aspects. Results: (1) Clinical efficacy: the total effective rate was 68.4 in the western medicine group, 61.5 in the traditional Chinese medicine group and 83.8 in the traditional Chinese medicine group. The total effective rate of the three groups after treatment was significantly different (P0.05), the curative effect of the combination group was significant. (2) after the treatment of TCM single symptom integral: the three groups after treatment cough, expectoration, pharyngitic itch symptom score were reduced compared with before treatment, The decrease order of cough symptom integral was: Chinese medicine group, western medicine group, Chinese medicine group, the difference was statistically significant (P0.05); expectoration symptom score reduction order was: traditional Chinese medicine group, western medicine group, Chinese medicine group, western medicine group and western medicine group, the order was: traditional Chinese medicine group, western medicine group, and western medicine group. The difference between the two groups was statistically significant (P0.05); the order of the decrease in the score of pharyngotic symptoms, the traditional Chinese medicine combined with western medicine group, the Western medicine group, the Chinese medicine group, the western medicine group, The difference between groups was statistically significant (P0.05). (3) after treatment of TCM syndromes total integral: the three groups after treatment TCM syndrome total score was statistically significant difference compared with before treatment (P0.05); traditional Chinese medicine combined with Chinese medicine syndromes total score decreased more significantly, There was no significant difference in the total score of TCM syndromes between the Chinese medicine group and the western medicine group (P0.05). Conclusion: Feiketing mixture and Asmex can improve the clinical symptoms of patients with cough after wind-induced lung infection. The combined treatment can relieve cough and expectoration more effectively and improve the clinical efficacy. In terms of clinical efficacy, Feiketing mixture and Asmectin have the same curative effect. The treatment of cough, expectoration, pharyngoitch and other symptoms with Feiketing mixture combined with asmetamine has a significant effect on cough after wind-induced pulmonary infection.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R56
本文编号：2276351
[Abstract]:Objective: to observe the clinical effect of Feiketing mixture (FKT) combined with Asmet in treating cough after wind-pathogenic lung infection, and to explore its mechanism, and to provide some clinical basis for the treatment of wind-pathogenic pulmonary infection with combined TCM and western medicine. Methods: from January 2015 to December 2016, 120 patients with cough after wind-induced pulmonary infection in Department of Respiratory Medicine, the first Hospital of Wuhan, were selected as study objects. These patients were randomly divided into western medicine group and combined Chinese and western medicine group. The western medicine group was treated with Asmectin (compound methoxifen), the traditional Chinese medicine group was treated with the Feiketan mixture, and the Chinese and western medicine combination group was treated with the combination of the Chinese medicine and the western medicine. The course of treatment was 10 days. After 10 days of treatment, the clinical efficacy, the change of TCM single symptom integral and the total score of TCM syndromes were observed, and the safety was evaluated. Statistical software was used to analyze the statistical differences of these clinical observation indexes, to compare the effective rate of Asmat, Feiketing mixture, and the combination of the two drugs in the treatment of lung type infection caused by wind evil, and to treat cough, expectoration and phlegm among the three groups. The therapeutic effect of pharynx itching and other aspects. Results: (1) Clinical efficacy: the total effective rate was 68.4 in the western medicine group, 61.5 in the traditional Chinese medicine group and 83.8 in the traditional Chinese medicine group. The total effective rate of the three groups after treatment was significantly different (P0.05), the curative effect of the combination group was significant. (2) after the treatment of TCM single symptom integral: the three groups after treatment cough, expectoration, pharyngitic itch symptom score were reduced compared with before treatment, The decrease order of cough symptom integral was: Chinese medicine group, western medicine group, Chinese medicine group, the difference was statistically significant (P0.05); expectoration symptom score reduction order was: traditional Chinese medicine group, western medicine group, Chinese medicine group, western medicine group and western medicine group, the order was: traditional Chinese medicine group, western medicine group, and western medicine group. The difference between the two groups was statistically significant (P0.05); the order of the decrease in the score of pharyngotic symptoms, the traditional Chinese medicine combined with western medicine group, the Western medicine group, the Chinese medicine group, the western medicine group, The difference between groups was statistically significant (P0.05). (3) after treatment of TCM syndromes total integral: the three groups after treatment TCM syndrome total score was statistically significant difference compared with before treatment (P0.05); traditional Chinese medicine combined with Chinese medicine syndromes total score decreased more significantly, There was no significant difference in the total score of TCM syndromes between the Chinese medicine group and the western medicine group (P0.05). Conclusion: Feiketing mixture and Asmex can improve the clinical symptoms of patients with cough after wind-induced lung infection. The combined treatment can relieve cough and expectoration more effectively and improve the clinical efficacy. In terms of clinical efficacy, Feiketing mixture and Asmectin have the same curative effect. The treatment of cough, expectoration, pharyngoitch and other symptoms with Feiketing mixture combined with asmetamine has a significant effect on cough after wind-induced pulmonary infection.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R56
【参考文献】
相关期刊论文 前10条
1 何雪梅;卢育明;;感染后咳嗽气道神经源性炎症水平与肺功能相关性研究[J];中国医学创新;2014年19期
2 王云方;朱佳;;浅述中西医对感染后咳嗽发病机制的认识[J];西部中医药;2014年05期
3 庄艳姗;;宣肺解表法治疗感冒后咳嗽疗效观察[J];中国现代医生;2013年17期
4 何婷;汤奇;曾南;苟玲;刘金伟;杨靖;于柳;王哲;龚锡平;;荆芥挥发油及其主要成分抗流感病毒作用与机制研究[J];中国中药杂志;2013年11期
5 王莘智;贺选玲;韩彬;范伏元;;止嗽散治疗感冒后咳嗽临床观察[J];中国中医药现代远程教育;2012年14期
6 辛瑾琛;;运用止嗽散治疗感染后咳嗽思路[J];今日药学;2012年06期
7 何婷;陈恬;曾南;汤奇;苟玲;刘金伟;彭希;于柳;;荆芥挥发油体外抗甲型流感病毒作用及机制的研究[J];中药药理与临床;2012年03期
8 汤奇;杨发龙;曾南;何婷;于柳;苟玲;彭希;刘金伟;;荆芥挥发油及其主要成分抗流感病毒作用研究[J];中药药理与临床;2012年02期
9 潘风琴;;针刺治疗感冒后咳嗽[J];山西中医;2012年01期
10 孙伟岳;金宏杰;;免煎饮片加味止嗽颗粒治疗感冒后咳嗽61例[J];浙江中医杂志;2011年10期
相关会议论文 前1条
1 张忠德;张溪;;小青龙汤加减配合雷火灸治疗感冒后咳嗽疗效观察[A];全国中医内科肺系病第十四次学术研讨会论文集[C];2010年
相关硕士学位论文 前1条
1 林汉军;吸入低浓度SO_2对大鼠气道炎症，，气道反应性和感觉神经的影响[D];第四军医大学;2007年
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