高血压性脑出血患者术后下呼吸道感染病原菌分布特征及相关因素分析

发布时间：2018-10-18 10:21

【摘要】：目的了解高血压性脑出血患者术后下呼吸道感染的病原菌分布特征,并分析引发下呼吸道感染的相关危险因素。方法对2015年8月-2016年8月医院1000例高血压性脑出血患者术后临床资料进行回顾性分析,对医院感染率、病原菌分布特征、下呼吸道感染的危险因素进行分析。结果 1 000例高血压性脑出血患者术后发生下呼吸道感染143例,感染率为14.30%;143例下呼吸道感染患者中,83例痰培养阳性,阳性率为58.04%;共分离出病原菌224株,其中革兰阴性菌142株占63.39%,革兰阳性菌48株占21.43%,真菌34株占15.18%;单因素分析显示,年龄≥65岁、有侵入性诊疗、住院时间14d、血糖水平7.8mmol/L、合并基础性疾病者下呼吸道感染率明显高于年龄65岁、无侵入性诊疗、住院时间≤14d、血糖水平≤7.8mmol/L、无基础性疾病者,差异有统计学意义(P0.05);年龄、侵入性诊疗、住院时间、血糖水平、基础性疾病是高血压性脑出血患者术后下呼吸道感染独立危险因素。结论高血压性脑出血患者术后下呼吸道感染率较高,以革兰阴性菌感染为主,应加强抗菌药物的合理应用,针对其相关因素进行预防,对降低下呼吸道感染具有重要作用。
[Abstract]:Objective to investigate the distribution of pathogens of lower respiratory tract infection in patients with hypertensive intracerebral hemorrhage after operation, and to analyze the risk factors of lower respiratory tract infection. Methods the clinical data of 1000 patients with hypertensive intracerebral hemorrhage from August 2015 to August 2016 were retrospectively analyzed. The nosocomial infection rate, the distribution of pathogenic bacteria and the risk factors of lower respiratory tract infection were analyzed. Results 143 cases of lower respiratory tract infection occurred in 1 000 patients with hypertensive intracerebral hemorrhage, the infection rate was 14.30% and 143 cases of lower respiratory tract infection, 83 cases were positive in sputum culture, the positive rate was 58.04, 224 strains of pathogenic bacteria were isolated. Among them, 142 strains of Gram-negative bacteria accounted for 63.39%, 48 strains of Gram-positive bacteria accounted for 21.43 and 34 strains of fungi accounted for 15.18.The univariate analysis showed that the age 鈮，

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