运动试验后心率恢复与稳定期慢性阻塞性肺疾病患者运动耐力的相关性研究

发布时间：2018-11-10 07:14

【摘要】：目的研究运动试验后心率恢复与慢性阻塞性肺疾病(COPD)患者疾病严重程度相关性,评估心率恢复对COPD患者运动耐力的影响。方法对60例稳定期COPD患者及50例健康志愿者做动脉血气分析、常规肺功能测定和心肺运动试验,并根据运动后心率恢复情况COPD患者分为心率恢复正常组(41例)和异常组(19例)。结果 COPD患者的运动耐力(峰值摄氧量占预计值百分比)、峰值心率、心率恢复明显低于正常组,分别为(66±15)比(89±11)、(134±21)比(149±13)次/min和(18±9)比(27±10)次/min,均P0.01,静息心率明显高于正常组[(83±13)比(77±13)次/min,P0.01]。心率恢复异常组较正常组第1秒用力呼气容积占预计值百分比和峰值摄氧量占预计值的百分比下降更显著,分别为(38±15)比(52±16)(P0.05)和(57±12)比(71±14)(P0.01)。心率恢复与第一秒用力呼气容积占预计值百分比和峰值摄氧量占预计值百分比呈显著性相关(r=0.422,P0.01和r=0.523,P0.01)。多变量回归分析显示,第1秒用力呼气容积占预计值百分比和心率恢复是预测COPD患者运动耐力的独立变量(P0.01和P=0.012)。结论运动后心率恢复不仅与COPD患者疾病严重程度相关,而且可作为预测COPD患者运动耐力的独立预测指标。
[Abstract]:Objective to study the relationship between the recovery of heart rate after exercise test and the severity of chronic obstructive pulmonary disease (COPD) patients, and to evaluate the effect of heart rate recovery on exercise endurance in patients with chronic obstructive pulmonary disease (COPD). Methods Arterial blood gas analysis, routine lung function test and cardiopulmonary exercise test were performed in 60 patients with stable COPD and 50 healthy volunteers. According to the recovery of heart rate after exercise, COPD patients were divided into normal group (41 cases) and abnormal group (19 cases). Results the exercise endurance (percentage of peak oxygen uptake), peak heart rate and heart rate recovery of COPD patients were (66 卤15) vs (89 卤11), (134 卤21) vs (149 卤13) / min and (18 卤9) vs (27 卤10) times / min, respectively. The resting heart rate was significantly higher than that in the normal group [(83 卤13) vs (77 卤13) / min,P0.01]. The percentage of forced expiratory volume to predicted value and the percentage of peak oxygen uptake to predicted value were significantly lower in abnormal heart rate recovery group than those in normal group, which were (38 卤15) vs (52 卤16) (P0.05) and (57 卤12) vs (71 卤14) (P0.01), respectively. Heart rate recovery was significantly correlated with the percentage of forced expiratory volume in the first second and the percentage of peak oxygen uptake in the predicted value (r = 0.422, P 0.01, r = 0.523, P 0.01). Multivariate regression analysis showed that the percentage of forced expiratory volume in the first second and the recovery of heart rate were independent variables to predict the exercise endurance of COPD patients (P0.01 and P0. 012). Conclusion the recovery of heart rate after exercise is not only related to the severity of COPD, but also can be used as an independent predictor of exercise endurance in COPD patients.
【作者单位】：同济大学附属上海市肺科医院肺功能室;
【分类号】：R563.9

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