慢性阻塞性肺疾病稳定期患者体重指数与肺功能的相关性
发布时间:2018-11-22 19:54
【摘要】:目的:探讨慢性阻塞性肺疾病(chronic obstructive pulmonary diseaseCOPD)稳定期患者的体重指数(body mass index BMI)和肺功能指标之间的相关性。 方法:收集2011年1月-2012年12月于我院门诊及住院治疗的COPD稳定期患者的肺功能相关指标,并按体重指数(BMI)分为3组,BMI<18.5kg/m2为低体重组,18.5kg/m2≤BMI<23.9kg/m2为正常体重组,BMI≥23.9kg/m2为高体重组。比较三组患者的肺功能障碍程度的发生率,分析BMI与肺功能指标之间的相关性。 结果:根据收集的111例慢性阻塞性肺疾病稳定期患者肺功能的结果分析,用力肺活量(forced vital capacity,,FVC)和BMI呈正相关(r=0.196,p0.05),第1秒用力呼气量占预计值的百分比(forced expiratory volume in on second,FEV1%)和BMI呈正相关(r=0.295, P 0.01),第1秒用力呼气量占用力肺活量的比值(FEV1/FVC)和BMI呈正相关(r=0.505, P 0.01),最大呼气中段流量(maximal mid-expiratory flow curve,MMEF)和BMI呈正相关(r=0.264,P 0.01)。低体重组分别与正常体重组、高体重组的肺功能障碍程度发生率比较均具有统计学意义(P 0.01),而正常体重组和高体重组的肺功能障碍程度发生率比较无统计学意义(P0.05)。低体重组分别与正常体重组、高体重组比较,在FVC, FEV1%,FEV1/FVC,MMEF指标间的差异均具有统计学意义(P 0.01);而正常体重组和高体重组相比,在FVC, FEV1%,FEV1/FVC,MMEF指标上的差异均无统计学意义(P0.05)。 结论:慢性阻塞性肺疾病稳定期患者肺功能指标如FVC, FEV1%,FEV1/FVC及MMEF均与患者的体重指数存在相关性,而体重指数与FEV1/FVC的相关性是这些指标中最显著地。COPD患者的体重指数和肺功能障碍程度有一定的相关性,低体重指数组肺功能障碍程度较正常体重组和高体重组严重。同时,低体重组的FVC,FEV1%,FEV1/FVC,MMEF均低于正常体重组、高体重组,而正常体重组和高体重组在肺功能的相关指标之间存在的差异无明显意义。改善COPD患者的营养状况,可以在一定程度上改善COPD患者肺功能和呼吸困难,提高生活质量。
[Abstract]:Objective: to investigate the correlation between body mass index (body mass index BMI) and pulmonary function in patients with chronic obstructive pulmonary disease (chronic obstructive pulmonary diseaseCOPD). Methods: lung function related indexes were collected from outpatients and inpatients with COPD in our hospital from January 2011 to December 2012, and were divided into three groups according to body mass index (BMI). BMI < 18.5kg/m2 was low weight group. 18.5kg/m2 鈮
本文编号:2350384
[Abstract]:Objective: to investigate the correlation between body mass index (body mass index BMI) and pulmonary function in patients with chronic obstructive pulmonary disease (chronic obstructive pulmonary diseaseCOPD). Methods: lung function related indexes were collected from outpatients and inpatients with COPD in our hospital from January 2011 to December 2012, and were divided into three groups according to body mass index (BMI). BMI < 18.5kg/m2 was low weight group. 18.5kg/m2 鈮
本文编号:2350384
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