146例孤立性肺结节的临床分析

发布时间：2018-11-23 08:30

【摘要】：目的探讨孤立性肺结节(SPN)的临床及影像学表现与鉴别SPN良恶性的关系。方法回顾性分析明确病理诊断的典型的SPN患者146例,按SPN直径分为3组,其中直径小于或等于0.8cm 16例、0.8~1.5cm 41例、1.5~3.0cm 89例。搜集患者的年龄、性别、吸烟史、临床症状及影像学资料,分析其与SPN良恶性的关系。结果全组146例均获病理学诊断,术后病理良性病变52例(35.6%),恶性病变94例(64.4%)。随SPN直径的增大,恶性比率有明显增高趋势。患者有吸烟史及临床症状在良恶性病变中的数据差异有统计学意义(P0.05)。SPN界限是否清楚、有无分叶、毛刺、胸膜凹陷征及血管集束征在良恶性病变中的数据差异均有统计学意义(P0.05)。结论 SPN的临床及影像学特征性表现对其良恶性的判断有重要的参考价值,积极干预SPN对提高肺癌生存率意义重大。
[Abstract]:Objective to investigate the relationship between clinical and imaging features of solitary pulmonary nodules (SPN) and differential diagnosis of benign and malignant SPN. Methods 146 patients with typical SPN diagnosed by pathology were retrospectively analyzed and divided into 3 groups according to the diameter of SPN, including 16 cases with diameter less than or equal to 0.8cm, 41 cases with 0.8~1.5cm and 89 cases with 1.5~3.0cm. Age, sex, smoking history, clinical symptoms and imaging data were collected to analyze the relationship between age, sex, smoking history, and benign and malignant SPN. Results all 146 cases were diagnosed by pathology. 52 cases (35.6%) had benign pathological changes and 94 cases (64.4%) had malignant lesions. With the increase of SPN diameter, the malignant ratio increased obviously. There were statistically significant differences in the data of smoking history and clinical symptoms in benign and malignant lesions (P0.05). (P0.05) the boundary of). SPN was clear, whether there were lobes, burrs, or not. The data of pleural depression sign and vascular cluster sign in benign and malignant lesions were significantly different (P0.05). Conclusion the clinical and imaging features of SPN have important reference value for the diagnosis of benign and malignant tumors. It is of great significance to improve the survival rate of lung cancer by actively intervening in SPN.
【作者单位】：江苏省南通市第一人民医院呼吸科;
【分类号】：R563

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