稳定期慢性阻塞性肺疾病患者运动能力的影响因素分析
发布时间:2018-12-15 12:29
【摘要】:【目的】探讨影响稳定期慢性阻塞性肺疾病(COPD)患者运动能力的主要因素。【方法】检测109例稳定期COPD患者常规肺通气功能、股四头肌功能和在6 min步行试验(6MWT)前后深吸气量(IC)的变化,同时对所有受试者进行改良版英国医学研究会(m MRC)呼吸困难评分、圣乔治呼吸问卷(SGRQ)、匹兹堡睡眠质量指数(PSQI)量表、Epworth嗜睡量表(ESS)及汉密尔顿焦虑量表(HAMA)和抑郁量表(HAMD)评估。【结果】多元逐步线性回归分析结果表明,年龄(标准化系数β=-0.264,P=0.007)、HAMD评分(β=-0.246,P=0.005)、SGRQ活动部分评分(β=-0.194,P=0.029)和股四头肌力量(β=0.197,P=0.030)对COPD患者6 min步行距离(6MWD)有显著预测意义。【结论】年龄、抑郁、日常活动能力和股四头肌力量可能是稳定期COPD患者运动能力的主要影响因素。
[Abstract]:[objective] to investigate the main factors affecting the motor ability of patients with (COPD) in stable stage. [methods] to detect the routine pulmonary ventilation function in 109 patients with stable COPD. The function of quadriceps femoris and the changes of inspiratory (IC) before and after 6 min walking test (6MWT) were performed on all subjects with an improved (m MRC) dyspnea score of the British Medical Society, St. George's Respiratory questionnaire (SGRQ), Pittsburgh Sleep quality Index (PSQI), Epworth somnolence scale (ESS), Hamilton anxiety scale (HAMA) and Depression scale (HAMD) were evaluated. Age (standardized coefficient 尾 = -0.264) Pao 0.007), HAMD score (尾 = -0.246 Pao 0.005), SGRQ activity part score (尾 = -0.194 pectoris 0.029) and quadriceps femoris strength (尾 = 0.197), [conclusion] Age, depression, activity of daily activities and quadriceps femoris might be the main factors influencing the motor ability of patients with COPD at stable stage.
【作者单位】: 中山大学孙逸仙纪念医院呼吸内科;中山大学孙逸仙纪念医院综合科;
【基金】:广东省科技计划项目(2011B080701062) 广东省自然科学基金(S2012010008623)
【分类号】:R563.9
[Abstract]:[objective] to investigate the main factors affecting the motor ability of patients with (COPD) in stable stage. [methods] to detect the routine pulmonary ventilation function in 109 patients with stable COPD. The function of quadriceps femoris and the changes of inspiratory (IC) before and after 6 min walking test (6MWT) were performed on all subjects with an improved (m MRC) dyspnea score of the British Medical Society, St. George's Respiratory questionnaire (SGRQ), Pittsburgh Sleep quality Index (PSQI), Epworth somnolence scale (ESS), Hamilton anxiety scale (HAMA) and Depression scale (HAMD) were evaluated. Age (standardized coefficient 尾 = -0.264) Pao 0.007), HAMD score (尾 = -0.246 Pao 0.005), SGRQ activity part score (尾 = -0.194 pectoris 0.029) and quadriceps femoris strength (尾 = 0.197), [conclusion] Age, depression, activity of daily activities and quadriceps femoris might be the main factors influencing the motor ability of patients with COPD at stable stage.
【作者单位】: 中山大学孙逸仙纪念医院呼吸内科;中山大学孙逸仙纪念医院综合科;
【基金】:广东省科技计划项目(2011B080701062) 广东省自然科学基金(S2012010008623)
【分类号】:R563.9
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