支气管舒张试验在小气道病变患者中的临床应用价值

发布时间：2019-03-02 15:36

【摘要】：目的探讨支气管舒张试验在小气道病变患者中临床应用方面的价值,观察其对早期支气管哮喘有无预测价值。方法根据小气道病变诊断标准选取郑州大学第五附属医院门诊及住院部的104例小气道病变患者,观察所有患者支气管舒张试验的结果,并追踪患者病情转归。结果 104例患者中有33例阳性,71例阴性。阳性组和阴性组舒张前FEF25-75%、FEF50%(V50%)、FEF75%(V25%)比较差异有统计学意义(P0.05),舒张前FEF25-75%、FEF50%(V50%)、FEF75%(V25%)与FEV1改善率和增加量均呈负相关。33例支气管舒张试验阳性患者中有23例患者确诊为支气管哮喘,小气道病变患者的支气管哮喘的发生率为21.02%。结论支气管哮喘可能多合并小气道病变,考虑小气道病变患者应早期行支气管舒张试验,该试验在小气道病变患者中的应用对支气管哮喘的发生可能有预测价值。
[Abstract]:Objective to investigate the clinical value of bronchodilation test in patients with small airway disease and to observe the predictive value of bronchodilation test in the early stage of bronchial asthma. Methods according to the diagnostic criteria of small airway disease, 104 patients with small airway disease were selected from the outpatient and inpatient departments of the Fifth affiliated Hospital of Zhengzhou University. The results of bronchodilation test were observed in all patients, and the prognosis of the patients was followed up. Results 33 of 104 patients were positive and 71 were negative. The pre-diastolic FEF25-75%,FEF50% (V50%) and FEF75% (V25%) were significantly different between the positive group and the negative group (P0.05), and the pre-diastolic FEF25-75%,FEF50% (V50%) was significantly different between the positive group and the negative group. There was a negative correlation between FEF75% (V25%) and the improvement rate and increase of FEV1. Among 33 patients with positive bronchodilation test, 23 patients were diagnosed as bronchial asthma, and the incidence of bronchial asthma in patients with small airway disease was 21.02%. Conclusion bronchial asthma may be associated with small airway disease. Early bronchodilation test should be performed in patients with small airway disease. The application of this test in patients with small airway disease may be of predictive value for the occurrence of bronchial asthma.
【作者单位】：郑州大学第五附属医院呼吸内科;
【分类号】：R562.25

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