川蛭通络胶囊联合头孢呋辛治疗成人大叶性肺炎的临床效果观察

发布时间：2019-03-03 11:00

【摘要】：目的:观察川蛭通络胶囊联合头孢呋辛治疗成人大叶性肺炎的临床效果。方法:纳入2014年4月至2015年7月我院收治的患大叶性肺炎的成人患者104例,按随机数字表法分为观察组和对照组各52例。对照组给予头孢呋辛治疗,观察组患者在对照组基础上加用川蛭通络胶囊联合治疗。记录并分析两组患者治疗前和治疗后两周相关症状的消失时间、炎症水平、血浆白细胞水平和中性粒细胞比例以及治疗疗效。结果:观察组发热消失时间、肺部Up音消失时间和咳嗽消失时间分别为(4.65±0.47、6.75±0.54、5.93±0.58)d,均显著短于对照组(6.02±0.59、8.06±0.83、8.46±0.76)d。观察组治疗后血清超敏C反应蛋白(hsCRP)和降钙素原(PCT)水平分别为(19.43±2.86mg/L、1.15±0.42ng/L),均明显低于对照组(30.57±3.49mg/L、2.13±0.57ng/L)。3观察组治疗后白细胞水平和中性粒细胞比例分别为(9.62±0.48×109/L、70.53±2.41%),均明显低于对照组(10.98±0.59×109/L、78.62±3.05%);4观察组治疗后总有效率为94.23%,显著高于对照组78.85%。结论:川蛭通络胶囊联合头孢呋辛可有效治疗成人大叶性肺炎,调节患者体内炎症水平,提高治疗效率。
[Abstract]:Objective: to observe the clinical effect of Chuanzhi Tongluo capsule combined with cefuroxime on adult lobar pneumonia. Methods: 104 adult patients with lobar pneumonia admitted to our hospital from April 2014 to July 2015 were randomly divided into two groups: observation group (n = 52) and control group (n = 52). The control group was treated with cefuroxime. The patients in the observation group were treated with Chuanzhi Tongluo capsule on the basis of the control group. The disappearance time, inflammatory level, plasma leukocyte level and neutrophil ratio before and two weeks after treatment were recorded and analyzed in the two groups. Results: the disappearance time of fever, pulmonary Up sound and cough in the observation group were (4.65 卤0.47), 6.75 卤0.54 and 5.93 卤0.58 days respectively, which were significantly shorter than those in the control group (6.02 卤0.59, 8.06 卤0.83, 8.46 卤0.76 d). The levels of serum high-sensitivity C-reactive protein (hsCRP) and procalcitonin (PCT) (19.43 卤2.86 mg / L, 1.15 卤0.42 ng/L) in the observation group after treatment were significantly lower than those in the control group (30.57 卤3.49 mg / L). 3After treatment, the leukocyte level and neutrophil ratio in the observation group (9.62 卤0.48 脳 109 mL, 70.53 卤2.41%) were significantly lower than those in the control group (10.98 卤0.59 脳 109 mL, 78.62 卤3.05%). 4 the total effective rate of observation group was 94.23%, which was significantly higher than that of control group (78.85%). Conclusion: Chuanzhi Tongluo capsule combined with cefuroxime can effectively treat adult lobar pneumonia, regulate the inflammatory level and improve the therapeutic efficiency.
【作者单位】：海口市第四人民医院;
【分类号】：R563.1

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