医院获得性肺炎预后及鲍氏不动杆菌感染危险因素分析
发布时间：2019-03-15 12:37
【摘要】：目的对医院患者感染鲍氏不动杆菌(AB)发生的医院获得性肺炎(HAP)的危险因素和HAP患者的预后进行回顾性分析,为预防和治疗医院获得性肺炎尤其是鲍氏不动杆菌感染的HAP提供依据。方法选取2014年1月-2015年12月医院HAP患者114例,通过多元logistic回归因素进行分析,评价HAP患者感染鲍氏不动杆菌的危险因素与HAP预后相关的危险因素。结果 114例HAP患者中发生呼吸机相关性肺炎15例,痰培养为鲍氏不动杆菌29例,患者病死率为43.0%;感染前30天内入住ICU、机械通气、使用碳青霉烯类抗菌药物为感染鲍氏不动杆菌的HAP独立危险因素;感染时APACHEII评分18、合并ARDS、合并休克是HAP死亡的独立危险因素。结论对于ICU患者、有机械通气史患者要警惕鲍氏不动杆菌感染风险,尽量减少ICU住院日及机械通气时间;临床上滥用碳青霉烯类抗菌药物会增加住院患者感染鲍氏不动杆菌风险,HAP患者感染时APACHEⅡ评分可以预估患者的预后。
[Abstract]:Objective to analyze retrospectively the risk factors of hospital acquired pneumonia (HAP) in patients with Acinetobacter baumannii (AB) infection and the prognosis of HAP patients. To provide evidence for the prevention and treatment of HAP in hospital-acquired pneumonia, especially Acinetobacter baumannii infection. Methods from January 2014 to December 2015, the risk factors of Acinetobacter baumannii infection in patients with HAP were evaluated by multivariate logistic regression analysis. The risk factors associated with the prognosis of HAP were evaluated in 114 patients with HAP from January 2014 to December 2015. Results there were 15 patients with ventilator-associated pneumonia and 29 patients with Acinetobacter baumannii in sputum culture. The mortality of the patients with HAP was 43. 0%. ICU, mechanical ventilation was performed within 30 days before infection and carbapenems were used as independent risk factors for HAP infection of Acinetobacter baumannii, APACHEII score 18 and ARDS, combined with shock were independent risk factors for HAP death when infected with Acinetobacter baumannii (Acinetobacter baumannii). Conclusion for patients with ICU, the risk of Acinetobacter baumannii infection should be vigilant in patients with mechanical ventilation history, and the hospitalization days and mechanical ventilation time of ICU should be reduced as much as possible. Clinical abuse of carbapenems increases the risk of Acinetobacter baumannii infection in inpatients. The APACHE 鈪，
本文编号：2440630
[Abstract]:Objective to analyze retrospectively the risk factors of hospital acquired pneumonia (HAP) in patients with Acinetobacter baumannii (AB) infection and the prognosis of HAP patients. To provide evidence for the prevention and treatment of HAP in hospital-acquired pneumonia, especially Acinetobacter baumannii infection. Methods from January 2014 to December 2015, the risk factors of Acinetobacter baumannii infection in patients with HAP were evaluated by multivariate logistic regression analysis. The risk factors associated with the prognosis of HAP were evaluated in 114 patients with HAP from January 2014 to December 2015. Results there were 15 patients with ventilator-associated pneumonia and 29 patients with Acinetobacter baumannii in sputum culture. The mortality of the patients with HAP was 43. 0%. ICU, mechanical ventilation was performed within 30 days before infection and carbapenems were used as independent risk factors for HAP infection of Acinetobacter baumannii, APACHEII score 18 and ARDS, combined with shock were independent risk factors for HAP death when infected with Acinetobacter baumannii (Acinetobacter baumannii). Conclusion for patients with ICU, the risk of Acinetobacter baumannii infection should be vigilant in patients with mechanical ventilation history, and the hospitalization days and mechanical ventilation time of ICU should be reduced as much as possible. Clinical abuse of carbapenems increases the risk of Acinetobacter baumannii infection in inpatients. The APACHE 鈪，
本文编号：2440630
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