比较太极联合马来酸茚达特罗与传统运动联合马来酸茚达特罗治疗COPD的价值
发布时间：2019-04-19 22:52
【摘要】：背景慢性阻塞性肺疾病患者可以通过传统肺康复训练提高其运动功能和生活质量。但是,在设备场地条件匮乏的边远落后地区,传统肺康复训练难以普及。太极是一种不依赖设备的锻炼方式,在中国地区的中老年群体中广泛流行。太极与传统肺康复在治疗COPD患者方面效果是否相当尚缺乏大规模随机对照研究,本研究将比较太极与传统肺康复对改善COPD患者运动耐量,股四头肌功能和呼吸困难的价值。方法选取来自农村的120名未使用过支气管扩张剂的COPD患者,随机分配成太极组或传统康复组。患者经过2周的单纯茚达特罗吸入粉剂(150 ug,qd)治疗后,联合太极康复运动(一周5次,每次1小时)或传统康复运动(一周3次,每次1小时),为期12周。比较治疗后太极组与传统康复组的mMRC评分,六分钟步行试验(6MWT),股四头肌最大肌力(QMVC)及去脂体重指数(FFMI)。结果110名患者顺利完成试验,经过2周的单纯茚达特罗吸入粉剂(150ug,qd)治疗和12周的茚达特罗治疗联合太极或传统肺康复治疗后,两组患者mMRC,6MWT,QMVC均有显著改善。QMVC较单纯茚达特罗治疗分别提高了3.8±5.6kg和4.9±4.3kg(p=0.373);6MWT分别增加了19.2±30m和23.1±31.3m(p=0.758);mMRC分别下降了0.44±0.57和0.57±0.54,(p=0.654);FFMI变化分别为-0.02±0.23和0.09±0.33,(p=0.446)。虽然两组病人的各项指标均得到改善,但改善程度在两组之间无明显差异。结论太极康复在改善COPD患者的运动耐量、下肢力量、减轻呼吸困难症状方面与传统肺康复相同,可作为传统肺康复的替代方式。
[Abstract]:Background patients with chronic obstructive pulmonary disease can improve their motor function and quality of life through traditional lung rehabilitation training. However, the traditional lung rehabilitation training is difficult to popularize in the remote and backward areas where the equipment site is scarce. Taiji is a device-independent exercise that is popular among middle-aged and elderly people in China. There is no large-scale randomized controlled study on the efficacy of Taiji and traditional pulmonary rehabilitation in the treatment of patients with COPD. This study will compare the value of Taiji and traditional pulmonary rehabilitation in improving exercise tolerance, quadriceps femoris function and dyspnea in patients with COPD. Methods 120 COPD patients without bronchodilator were randomly assigned to Taiji group or traditional rehabilitation group. The patients were treated with Indadilol inhalation powder (150 ug,qd) for 2 weeks, combined with Taiji rehabilitation exercise (5 times a week, 1 hour each) or traditional rehabilitation exercise (3 times a week, 1 hour per week) for 12 weeks. MMRC scores, six-minute walking test (6MWT), maximum muscle strength of quadriceps femoris and body mass index (FFMI).) of quadriceps femoris were compared between Taiji group and traditional rehabilitation group after treatment. Results the trial was successfully completed in 110 patients. After 2 weeks of inhalation of indomethacin powder (150 ug, QD) and 12 weeks of indendiolol therapy combined with Taiji or traditional lung rehabilitation therapy, the two groups of patients with mMRC,6MWT, were treated with Indadilol inhalation powder (150 ug, QD) alone and indendiolol for 12 weeks. QMVC was increased by 3.8 卤5.6kg and 4.9 卤4.3 kg (p < 0. 373), respectively, compared with that of indadrilol alone. The QMVC was improved significantly in all the patients (P < 0. 373). 6MWT increased by 19.2 卤30m and 23.1 卤31.3 m (P < 0. 758); mMRC decreased by 0.44 卤0.57 and 0.57 卤0. 54); FFMI, respectively,-0.02 卤0.23 and 0.09 卤0. 33respectively) (p = 0. 446). Although the indexes of the two groups were improved, there was no significant difference in the degree of improvement between the two groups. Conclusion Taiji rehabilitation is the same as traditional lung rehabilitation in improving exercise tolerance, lower limb strength and relieving dyspnea symptoms in COPD patients. It can be used as a substitute for traditional lung rehabilitation.
【学位授予单位】：广州医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R563.9
本文编号：2461363
[Abstract]:Background patients with chronic obstructive pulmonary disease can improve their motor function and quality of life through traditional lung rehabilitation training. However, the traditional lung rehabilitation training is difficult to popularize in the remote and backward areas where the equipment site is scarce. Taiji is a device-independent exercise that is popular among middle-aged and elderly people in China. There is no large-scale randomized controlled study on the efficacy of Taiji and traditional pulmonary rehabilitation in the treatment of patients with COPD. This study will compare the value of Taiji and traditional pulmonary rehabilitation in improving exercise tolerance, quadriceps femoris function and dyspnea in patients with COPD. Methods 120 COPD patients without bronchodilator were randomly assigned to Taiji group or traditional rehabilitation group. The patients were treated with Indadilol inhalation powder (150 ug,qd) for 2 weeks, combined with Taiji rehabilitation exercise (5 times a week, 1 hour each) or traditional rehabilitation exercise (3 times a week, 1 hour per week) for 12 weeks. MMRC scores, six-minute walking test (6MWT), maximum muscle strength of quadriceps femoris and body mass index (FFMI).) of quadriceps femoris were compared between Taiji group and traditional rehabilitation group after treatment. Results the trial was successfully completed in 110 patients. After 2 weeks of inhalation of indomethacin powder (150 ug, QD) and 12 weeks of indendiolol therapy combined with Taiji or traditional lung rehabilitation therapy, the two groups of patients with mMRC,6MWT, were treated with Indadilol inhalation powder (150 ug, QD) alone and indendiolol for 12 weeks. QMVC was increased by 3.8 卤5.6kg and 4.9 卤4.3 kg (p < 0. 373), respectively, compared with that of indadrilol alone. The QMVC was improved significantly in all the patients (P < 0. 373). 6MWT increased by 19.2 卤30m and 23.1 卤31.3 m (P < 0. 758); mMRC decreased by 0.44 卤0.57 and 0.57 卤0. 54); FFMI, respectively,-0.02 卤0.23 and 0.09 卤0. 33respectively) (p = 0. 446). Although the indexes of the two groups were improved, there was no significant difference in the degree of improvement between the two groups. Conclusion Taiji rehabilitation is the same as traditional lung rehabilitation in improving exercise tolerance, lower limb strength and relieving dyspnea symptoms in COPD patients. It can be used as a substitute for traditional lung rehabilitation.
【学位授予单位】：广州医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R563.9
【参考文献】
相关期刊论文 前1条
1 王月霞;莫家赐;成东海;刘豹;忽新刚;;太极拳运动对慢性阻塞性肺疾病患者生存质量和BODE指数的影响[J];中国康复医学杂志;2014年08期
，本文编号：2461363
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