纤维支气管镜吸痰治疗对重症肺部感染患者呼吸状态与炎性应激的影响研究

发布时间：2019-05-20 11:35

【摘要】：目的研究纤维支气管镜吸痰治疗对重症肺部感染患者呼吸状态与炎性应激的影响情况,以了解纤维支气管镜吸痰治疗在此类患者中的应用价值。方法选取2014年6月-2016年3月医院治疗46例重症肺部感染患者为研究对象,将46例患者随机分为对照组和观察组,每组各23例,对照组进行常规重症肺部感染治疗,观察组则在常规治疗的基础上再进行纤维支气管镜吸痰治疗,将两组患者治疗前和治疗后12h、24h及48h的呼吸状态与炎性应激指标进行比较。结果治疗后12h、24h及48h观察组肺功能指标FEV1、MMF及FVC水平分别为(2.24±0.18)L、(1.08±0.14)L/s、(2.68±0.21)L、(2.60±0.20)L、(1.24±0.16)L/s、(3.15±0.24)L及(2.84±0.23)L、(1.55±0.19)L/s、(3.36±0.27)L,其均好于对照组,其他呼吸相关指标也均好于对照组,血清炎性应激指标均低于对照组,差异均有统计学意义(P0.05)。结论纤维支气管镜吸痰治疗可有效地改善重症肺部感染患者的呼吸状态与炎性应激程度,因此在重症肺部感染患者中的应用价值较高。
[Abstract]:Objective to study the effect of fiberoptic bronchoscopy sputum aspiration therapy on respiratory state and inflammatory stress in patients with severe pulmonary infection, so as to understand the value of fiberoptic bronchoscopy sputum aspiration therapy in this kind of patients. Methods from June 2014 to March 2016, 46 patients with severe pulmonary infection were randomly divided into control group (n = 23) and observation group (n = 23). The control group was treated with routine severe pulmonary infection. The observation group was treated with fiberoptic bronchoscopy on the basis of routine treatment. The respiratory status of the two groups before treatment and 12 hours after treatment, 24 h and 48 h after treatment were compared with inflammatory stress indexes. Results at 12 hours and 48 hours after treatment, the levels of FEV1,MMF and FVC in the observation group were (2.24 卤0.18) L, (1.08 卤0.14) L 鈮，

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