脂联素在支气管哮喘中的作用
发布时间:2019-05-23 00:52
【摘要】:目的评估血清及诱导痰脂联素与哮喘炎症状态的关系。方法 42例哮喘患者按ACT评分分为控制不良组(ACT25分,n=24)、完全控制组(ACT=25分,n=18),10例健康人作对照组,检测其血清及诱导痰上清液中脂联素、白细胞介素-13(IL-13)的浓度、血清C反应蛋白(CRP)浓度并测量身高、体质量,计算体质量指数(BMI)。结果控制不良组血清及诱导痰脂联素、IL-13浓度、血清CRP浓度均高于完全控制组及对照组,差异均有统计学意义(P0.01),完全控制组诱导痰脂联素及血清IL-13浓度高于对照组,差异均有统计学意义(P0.05)。哮喘患者血清脂联素与血清CRP、血清IL-13正相关(r=0.51,P0.01;r=0.84,P0.01),诱导痰脂联素与血清CRP负相关(r=-0.52,P0.01)。结论在哮喘中脂联素与CRP、IL-13相关,其参与了哮喘的气道及全身炎症反应,是一种新的哮喘炎症标志物。
[Abstract]:Objective to evaluate the relationship between serum and induced sputum adiponectin and inflammatory state of asthma. Methods 42 patients with asthma were divided into poor control group (ACT25 score, n 鈮,
本文编号:2483447
[Abstract]:Objective to evaluate the relationship between serum and induced sputum adiponectin and inflammatory state of asthma. Methods 42 patients with asthma were divided into poor control group (ACT25 score, n 鈮,
本文编号:2483447
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