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雾化吸入多黏菌素治疗假单胞菌慢性感染的支气管扩张患者

发布时间:2019-06-03 05:56
【摘要】:正慢性呼吸道感染常常伴有慢性支气管扩张,多达四分之一的病例由铜绿假单胞菌引起,并可导致病情进展更快,病死率升高。Haworth等在支气管扩张伴铜绿假单胞菌感染(非囊胞性纤维化症)成年患者中,进行雾化吸入多黏菌素的疗效及耐受性研究。受试者为英国、俄罗斯及乌克兰等国的35个医疗中心、12个月内≥2次呼吸道标本中分离出铜绿假单胞菌的支气管扩张患者且纳入研究后21 d内出现感染
[Abstract]:Positive and chronic respiratory tract infections are often accompanied by chronic bronchiectasis, with up to 1/4 of cases caused by Pseudomonas aeruginosa and can lead to faster progress. Haworth et al studied the efficacy and tolerance of atomized inhaled polymyxin in adult patients with bronchiectasis complicated with Pseudomonas aeruginosa infection (non-cystocytic fibrosis). The subjects were 35 medical centers in Britain, Russia and Ukraine. Pseudomonas aeruginosa bronchiectasis was isolated from respiratory tract specimens 鈮,

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