探讨新建立的澳门脉冲振荡肺功能预计值方程式在老年COPD患者诊断中的价值

发布时间：2019-07-24 09:33

【摘要】：目的探讨新建立的澳门健康成人脉冲振荡肺功能各主要指标预计值方程式在老年COPD患者中的诊断价值。方法对97例老年COPD患者及47例健康老年人应用脉冲振荡肺功能测定气道阻力,与常规肺通气功能、新建立的澳门健康成人脉冲振荡肺功能各主要指标预计值和厂家预计值进行比较,对比分析它们对COPD的诊断价值。结果 COPD男女两组Zrs、R5、(R5-R20)、RF均高于健康对照组,男性COPD组R20亦高于健康对照组;X5、X20 COPD组均低于健康对照组。除女性组R5 A/P1(厂家预计值)与FEV1/FVC%、FEV1/Pre%相关性稍高外,余男女两组Zrs、R20、X5等指标均为P2(新建立的澳门健康成人脉冲振荡肺功能各主要指标预计值)与FEV1/FVC%、FEV1/Pre%相关性最高。RF、Zrs、(R5-R20)、R5、R20、X5(P2-A)等指标均与FEV1/FVC%、FEV1/Pre%呈显著负相关,其中RF的相关性最为密切,其余依次为女性组:Zrs(A/P2)、(R5-R20)、X5(P2-A)、R5、R20;男性组,与FEV1/FVC%相关的顺序为Zrs(A/P2)、X5(P2-A)、(R5-R20)、R5、R20。与FEV1/Pre%相关的顺序为X5(P2-A)、Zrs(A/P2)、(R5-R20)、R5、R20。IOS各指标ROC曲线下面积分析显示,Zrs(A/P2)、R5(A/P2)、R20(A/P2)、R20(A/P2)、X5(P2-A)分别大于Zrs(A/P1)及Zrs(A)、R5(A/P1)、R20(A/P1)、R20(A/P1)、X5(P1-A)。男性组Zrs(A/P2)%≥113.7时,R5(A/P2)%≥133.4时,R20(A/P2)%≥77.4时,X5(P2-A)≥0.035时,RF≥15.9时,各约登指数最高。女性组Zrs(A/P2)%≥127.7时,R5(A/P2)%≥121.7时,R20(A/P2)%≥129.5时,X5(P2-A)≥0.005时,RF≥18时,各约登指数最高。结论脉冲振荡肺功能对COPD具有诊断价值,根据澳门本地人群建立的正常预计值方程式在诊断COPD时,其敏感性、特异性均高于厂家预计值,建议推广应用。
[Abstract]:Objective to investigate the diagnostic value of the predicted values of pulse oscillatory pulmonary function in elderly patients with COPD. Methods Airway resistance was measured by pulse oscillatory pulmonary function in 97 elderly patients with COPD and 47 healthy elderly. The predicted values of main indexes and manufacturers of pulse oscillatory pulmonary function in healthy adults in Macao were compared with those of conventional pulmonary ventilation, and their diagnostic value for COPD was compared and analyzed. Results Zrs,R5, (R5-R20), RF) in both male and female groups of COPD was higher than that in healthy control group, R20 in male COPD group was also higher than that in healthy control group, and X5, X20 COPD group was lower than that in healthy control group. Except that the correlation between R5 A/P1 and FEV1/FVC%,FEV1/Pre% was slightly higher in the female group, the indexes such as Zrs,R20,X5 were P2 (the predicted values of the main indexes of pulse oscillatory lung function in healthy adults in Macao) were the highest correlation with FEV1/FVC%,FEV1/Pre%. RF, Zrs, (R5-R20), R5, R20, X5 (P 2 鈮，

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