蒙特利尔认知量表对脑白质疏松患者认知功能障碍的诊断价值

发布时间：2018-03-16 23:26

本文选题：认知功能障碍　切入点：脑白质疏松　出处：《中国老年学杂志》2017年23期 　论文类型：期刊论文

【摘要】：目的研究蒙特利尔认知(MoCA)量表在筛查脑白质疏松(LA)患者轻度认知功能障碍中的应用价值。方法 LA患者113例为LA组,同期健康体检者107例为对照组,分别采用MoCA量表及简易精神状态量表(MMSE)进行认知功能评估。结果除命名和视空间执行功能外,LA组MoCA各分项得分与对照组均有统计学差异(P0.01,P0.05);LA组与对照组MoCA评分差异有统计学意义(P0.05);MMSE评分差异无统计学意义(P0.05);两组MoCA和MMSE评分对比,MoCA灵敏度80.53%,特异度76.63%;MMSE灵敏度22.12%,特异度88.78%。MoCA灵敏度显著高于MMSE(P0.01)。结论 MoCA量表在诊断LA患者轻度认知功能损害中具有更高的灵敏度,可及早发现LA患者的认知功能损害。
[Abstract]:Objective to study the value of Montreal Cognitive moca scale in the screening of mild cognitive impairment in patients with leukoaraiosis. Methods 113 patients with LA and 107 healthy subjects as control group were enrolled in this study. The cognitive function of LA group was evaluated with MoCA scale and mini-mental state scale respectively. Results the scores of MoCA in LA group were significantly different from those in control group (P 0.01) and MoCA score in LA group was significantly different from that in control group. There was no significant difference in MMSE score between the two groups (P 0.05). The sensitivity and specificity of MoCA and MMSE were 80.53 and 22.12, respectively. The sensitivity of MoCA was significantly higher than that of MMSE P0.01.Conclusion in the diagnosis of mild cognitive function in LA patients, the sensitivity of MoCA scale is significantly higher than that of MMSE P0.01.Conclusion in the diagnosis of mild cognitive function in LA patients, the sensitivity of MoCA scale is significantly higher than that of MoCA scale. Higher sensitivity in damage, Cognitive impairment in LA patients can be detected as early as possible.
【作者单位】：郑州大学第五附属医院神经内科;
【基金】：河南省卫生厅重大科技攻关项目(No.WKJ2011-2019)
【分类号】：R749.13

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