前列腺基底细胞癌3例

发布时间：2018-01-01 22:33

本文关键词：前列腺基底细胞癌3例　出处：《北京大学学报(医学版)》2016年04期 　论文类型：期刊论文

【摘要】：探讨前列腺基底细胞癌(basal cell carcinoma,BCC)临床病理特点并提高诊疗认识。通过报道3例BCC患者的临床病理特点及诊疗经过,结合文献复习,提高对BCC诊疗特点的认识。3例BCC患者年龄为57~83岁,其中1例因血尿就诊,2例因排尿困难就诊。3例患者均合并前列腺增生,其中2例患者前列腺特异性抗原(prostate specific antigen,PSA)增高,1例PSA正常。病例1前列腺癌侵及膀胱、直肠前筋膜,伴淋巴结转移、骨转移、双肺多发转移,2014年11月2日行膀胱全切+双侧输尿管皮肤造口术+双侧闭孔及髂内淋巴结清扫术,术后病理诊断BCC,2015年1月8日复查盆腔增强MRI提示盆腔内复发,2015年7月11日复查腹部增强CT提示肝多发转移,胰腺转移,2015年10月因前列腺癌死亡。病例2于2015年3月27日行前列腺穿刺病理诊断为BCC,伴肺转移及骨转移,行化疗及内分泌治疗,后行局部放射治疗,2016年1月11日复查正电子发射断层显像与计算机断层显像(positron emission tomography and computed tomography,PET-CT)示患者肺转移瘤及骨转移瘤直径较前增大,数量增多,随访至2016年1月10日患者带瘤生存。病例3外院行经尿道前列腺电切术(transurethral resection of prostate,TURP),术后病理考虑BCC可能,行PET-CT提示残余前列腺恶性肿瘤,伴双侧盆腔淋巴结转移可能,2016年4月20日复查PET-CT提示盆腔可见巨大不规则混杂密度影,临床考虑肿瘤复发,遂予局部放射治疗,随访至2016年1月10日患者带瘤生存。BCC临床罕见,是一种侵袭能力强、恶性程度较高、易发生转移的肿瘤,需要给予积极的治疗和密切的随访。
[Abstract]:To investigate the basal cell carcinoma of basal cell carcinoma of the prostate. The clinicopathological characteristics and diagnosis and treatment of 3 cases of BCC were reported and reviewed in combination with literature review. The age of 3 BCC patients was 57 ~ 83 years old. One patient with hematuria and 2 patients with dysuria were all complicated with prostatic hyperplasia. Among them, 2 patients with prostate specific antigen specific antigen-PSAs increased in 1 case, PSA was normal in 1 case, and prostate cancer invaded bladder in case 1. Rectal anterior fascia, with lymph node metastasis, bone metastasis, multiple metastasis of both lungs. In November 2nd 2014, total cystectomy and bilateral ureterostomy were performed with bilateral obturator and internal iliac lymph node dissection. Postoperative pathological diagnosis of BCC, pelvic enhanced MRI on January 8th 2015 to indicate pelvic recurrence, abdominal CT on July 11th 2015 to indicate multiple liver metastasis, pancreatic metastasis. Case 2 died of prostate cancer on October 2015. Case 2 was diagnosed as BCC with lung metastasis and bone metastasis on March 27th 2015, and received chemotherapy and endocrine therapy. Then local radiotherapy was performed. In January 11th 2016, positron emission tomography and computed tomography (. Positron emission tomography and computed tomography. PET-CTS showed that the diameter and number of pulmonary metastases and bone metastases were larger and larger. Case 3 patients underwent transurethral resection of the prostate (TURP). Transurethral resection of prostate. TURP, BCC may be considered pathologically after operation, PET-CT suggests residual benign prostate neoplasms with bilateral pelvic lymph node metastasis. In April 20th 2016, PET-CT showed that large irregular mixed density could be seen in the pelvic cavity, and the recurrence of the tumor was considered clinically, and then local radiotherapy was given. Follow-up to January 10th 2016 patients with tumor survival. BCC clinical rare, is a strong invasive, high degree of malignancy, prone to metastasis, need to be actively treated and closely followed up.
【作者单位】：北京大学第三医院泌尿外科;北京大学第三医院病理科;北京大学第一医院泌尿外科;
【分类号】：R737.25
【正文快照】： 医院泌尿外科,北京100034)△Corresponding author’s e-mail,malulin@medmail.com.cnThen the patient received local radiation therapy.The patient survived in the followed upon January 10,2016.BCC of prostate is a rare subtype.Due to the local infiltrative and

【相似文献】