贝前列腺素钠联合复方玄驹胶囊治疗阴茎勃起功能障碍

发布时间：2018-01-03 05:40

本文关键词：贝前列腺素钠联合复方玄驹胶囊治疗阴茎勃起功能障碍　出处：《实用医学杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的:探讨贝前列腺素钠联合复方玄驹胶囊治疗阴茎勃起功能障碍(ED)的有效性及安全性。方法:将62例阴茎勃起功能障碍患者随机分为两组。观察组:32例,口服贝前列腺素钠(20μg/次,3次/d)及复方玄驹胶囊(3粒/次,3次/d);对照组:30例,口服同等剂量的复方玄驹胶囊及维生素E(10 mg/次,3次/d);疗程4周。观察患者治疗前后IIEF-5评分、阴茎海绵体血流量的变化,以及不良反应的发生。结果:两组较治疗前IIEF-5评分显著提高(P0.01),阴茎海绵体血流量明显增加(P0.01),而观察组在治疗后的评分及血流量均明显高于对照组(P0.05);在主观感受满意度上,观察组中明显高于对照组(P0.05);两组间不良反应比较无明显差异(P0.05)。结论 :贝前列腺素钠联合复方玄驹胶囊能显著改善ED患者的阴茎勃起功能。
[Abstract]:Objective: to explore the treatment of penile erectile dysfunction (EDD) with becprostaglandin sodium combined with compound Xuanju capsule. Methods: 62 patients with penile erectile dysfunction were randomly divided into two groups: observation group (n = 32). The patients were treated by oral administration of beprostaglandin sodium (20 渭 g / d) and compound Xuanju capsule (3 capsules / 3 / d). In the control group, 30 cases were given the same dose of compound Xuanju capsule and vitamin E 10 mg / time 3 times / d. The changes of IIEF-5 score and cavernous body blood flow were observed before and after treatment for 4 weeks. Results: compared with before treatment, the IIEF-5 score of the two groups increased significantly (P 0.01), and the blood flow of the corpus cavernosum increased significantly (P 0.01). The scores and blood flow of the observation group after treatment were significantly higher than that of the control group (P 0.05). In terms of subjective feeling satisfaction, the observation group was significantly higher than the control group (P 0.05); There was no significant difference in adverse reactions between the two groups (P 0.05). Conclusion: the penile erectile function of Ed patients can be significantly improved by the combination of beprostaglandin sodium and compound Xuanju capsule.
【作者单位】：中山大学附属第五医院泌尿外科;中山大学附属第五医院消化内科;
【分类号】：R698.1
【正文快照】： 阴茎勃起功能障碍(ED)是指持续性的出现阴茎不能达到和(或)保持充分勃起以致不能获得满意的性活动[1]。40岁以上男性有70%存在不同程度的勃起功能障碍,且发病率与年龄呈正相关。目前临床上常选用以万艾可为代表的5型磷酸二酯酶抑制剂治疗ED,但资料显示仍有部分ED患者对万艾可

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