经导管肾动脉化疗栓塞联合射频消融术治疗肾癌的疗效分析

发布时间：2018-02-01 09:49

本文关键词： 肾肿瘤化学栓塞治疗性导管消融联合治疗　出处：《中国介入影像与治疗学》2017年05期 　论文类型：期刊论文

【摘要】：目的评价TACE联合射频消融术(RFA)治疗肾癌的疗效。方法回顾性分析我中心收治的23例肾癌患者资料。全部患者均首先行肾TACE治疗,并在3~4周后在超声及CT的联合引导下行RFA术。评价患者术前术后的卡氏功能状态评分(KPS评分)及肾功能变化情况,同时在随访期内定期对患者行腹部超声、CT/MR增强扫描评价其疗效。结果至随访终止,全部23例患者中生存21例(21/23,91.30%),死亡2例(2/23,8.70%)。全部患者在术前和随访期结束时的KPS评分及血肌酐水平差异无统计学意义(P均0.05)。至随访结束,23例患者肾内病灶的治疗效果为完全缓解16例、部分缓解5例、进展2例。结论 TACE联合RFA治疗肾癌创伤小、疗效确切、围术期并发症少,是一种较为安全有效的方法。
[Abstract]:Objective to evaluate the efficacy of TACE combined with radiofrequency ablation (RFA) in the treatment of renal cell carcinoma (RCC). Methods the data of 23 RCC patients treated in our center were retrospectively analyzed. All patients were treated with renal TACE first. Three weeks later, RFA was performed under the combined guidance of ultrasound and CT. The changes of renal function and KPS were evaluated before and after operation. At the same time, during the follow-up period, the patients were regularly evaluated with CT / Mr enhanced CT / CT scan. Results to the end of follow-up, 21 of the 23 patients survived 21 / 23 / 91.300.Results: 1. There was no significant difference in KPS score and serum creatinine level between the two patients before operation and at the end of follow-up period (P < 0.05). There were 16 cases of complete remission, 5 cases of partial remission and 2 cases of progress. Conclusion TACE combined with RFA is less invasive, effective and less complication in perioperative period. It is a safe and effective method.
【作者单位】：北京大学第一医院介入血管外科;
【分类号】：R737.11
【正文快照】： 近年来,随着血管腔内介入治疗的迅速发展,TA-CE、射频消融术(radiofrequency ablation,RFA)已经成为临床治疗肾脏恶性肿瘤的常用方法。尤其对于体质差、合并症多、麻醉风险大或不愿接受手术切除的中晚期肾细胞癌(renal cell carcinoma,RCC)患者,介入治疗可有效抑制肿瘤生长、

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