维持性血液透析患者血管钙化及相关因素分析

发布时间：2018-02-16 04:08

本文关键词： 维持性血液透析血管钙化甲状旁腺激素　出处：《中国动脉硬化杂志》2015年06期 　论文类型：期刊论文

【摘要】：目的观察维持性血液透析(MHD)患者血管钙化情况及其影响因素,探讨矿物质与骨代谢指标在MHD患者血管钙化中的作用。方法选取MHD患者69例和健康体检者67例,检测血清白蛋白、血清总钙、血磷、血肌酐、碱性磷酸酶、钙磷乘积和全段甲状旁腺激素(i PTH)。同时行侧位腹平片(空腹)、髋关节正位片、双手及腕关节正位片X线检查以评价腹主动脉、股动脉、桡动脉及双手动脉钙化情况,并了解钙化与相关因素之间的关系。结果 MHD组血管钙化程度明显高于正常对照组(P0.05);中重度钙化组年龄、透析时间、血糖、血磷和钙磷乘积均高于轻度钙化组(P0.05);低i PTH(150 ng/L)、高i PTH(300 ng/L)患者i PTH与钙化相关(P0.05),150~300 ng/L i PTH患者i PTH与钙化无相关性(P0.05)。结论年龄、透析时间、血磷、血糖、钙磷乘积、i PTH水平可能与MHD患者血管钙化密切相关。
[Abstract]:Objective to observe the vascular calcification and its influencing factors in patients with maintenance hemodialysis (HD) and to explore the role of mineral and bone metabolism in vascular calcification in patients with MHD. Methods 69 patients with MHD and 67 healthy controls were selected to detect serum albumin. Serum total calcium, serum phosphorus, serum creatinine, alkaline phosphatase, calcium-phosphorus product and the whole parathyroid hormone (PTH). Results the degree of vascular calcification in the MHD group was significantly higher than that in the normal control group (P 0.05), the age, dialysis time, blood glucose in the moderate and severe calcification group were significantly higher than those in the normal control group. There was no correlation between I PTH and calcification in patients with low I PTH(150 ng / L, high I PTH(300 ng / L, P 0. 05%, P 0. 05 ng/L I PTH. Conclusion Age, dialysis time, blood phosphorus, blood glucose, blood glucose, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05. The level of calcium and phosphorus product I PTH may be closely related to vascular calcification in patients with MHD.
【作者单位】：南华大学附属第二医院肾内科;中南大学湘雅二医院肾病研究所;南华大学附属第二医院放射科;
【分类号】：R692.5

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