DiLEP与PKRP治疗BPH临床疗效对比分析

发布时间：2018-02-22 15:39

本文关键词： 良性前列腺增生症 980nm半导体激光前列腺剜除术前列腺切除术等离子　出处：《青海大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:本研究主要对比分析980nm半导体激光前列腺剜除术(Diode laser enucleation of the prostate,DiLEP)与经尿道前列腺等离子双极电切术(Transuretheral plasmakinetic resection of prostate,PKRP)治疗良性前列腺增生(benign prostatic hyperplasia,BPH)的安全性与有效性,为今后临床使用980nm半导体激光提供参考。方法:收集青海省人民医院泌尿外科2015年05月—2016年12月收住入院且手术的BPH患者病例资料,符合条件患者111例,其中55例行DiLEP,56例行PKRP,分别为DiLEP组和PKRP组。通过分析两组患者手术时间、术中失血量、围手术期并发症、术后膀胱冲洗时间、尿管留置时间及住院时间来评价两种术式的安全性;通过比较两组患者术前和术后3个月国际前列腺症状评分(IPSS)、生活质量指数评分(QOL)、最大尿流率(Qmax)、残余尿量(PVR)的差异来评价两种术式的有效性。结果:111例患者顺利完成手术及术后随访。DiLEP组与PKRP组术前年龄、病程、前列腺体积、IPSS、QOL、Qmax、PVR及血红蛋白等一般资料比较差异无统计学意义(P0.05);DiLEP组的手术时间与PKRP相比较差异无统计学意义(P0.05);DiLEP组术中的失血量明显少于PKRP组,差异有统计学意义(P0.05);术后DiLEP组膀胱冲洗时间、尿管留置时间、住院时间均明显少于PKRP组,差异有统计学意义(P0.05);DiLEP组术后并发症发生率与PKRP组相比,差异无统计学意义(P0.05);DiLEP组与PKRP组术后3个月时复查指标显示两组患LUTS均较术前明显改善,差异有统计学意义(P0.05);两组患者复查指标间进行比较,差异无统计学意义(P0.05)。结论:DiLEP与PKRP均是治疗BPH安全有效的手术方式,且在改善BPH患者的LUTS方面近期疗效相似。但DiLEP相比于PKRP具有围手术期出血少及术后恢复快。
[Abstract]:Objective: to compare the safety and efficacy of laser enucleation of the prostate enucleation with 980nm semiconductor laser in the treatment of benign prostatic hyperplasia (BPH) with transurethral plasmakinetic resection of prostatectomies. Methods: the data of BPH patients admitted to hospital from May 2015 to December 2016 in the Department of Urology of Qinghai Provincial people's Hospital were collected. The safety of the two groups was evaluated by analyzing the operation time, blood loss, perioperative complications, postoperative bladder irrigation time, urinary catheter retention time and hospitalization time. The effectiveness of the two methods was evaluated by comparing the differences of IPSS, QOLO, Qmaxus, PVR between the two groups before and 3 months after operation. Results 111 cases of patients were successfully completed. Age before operation and follow-up after operation. DiLEP group and PKRP group. There was no significant difference in the general data such as PVR and hemoglobin between the two groups. There was no significant difference in the operative time between the two groups. There was no significant difference between the two groups. The amount of blood loss during operation in the P0.05 Dilep group was significantly lower than that in the PKRP group. The postoperative bladder irrigation time, urinary catheter retention time and hospitalization time in DiLEP group were significantly lower than those in PKRP group, and the incidence of postoperative complications in P0.05 + DiLEP group was significantly lower than that in PKRP group. There was no significant difference between the two groups at 3 months after operation, the LUTS in the two groups were significantly improved compared with those before operation, and the difference was statistically significant (P 0.05), and the reexamination indexes were compared between the two groups. There was no significant difference (P 0.05). Conclusion both PKRP and VDLEP are safe and effective methods for the treatment of BPH, and the short-term curative effect in improving LUTS in BPH patients is similar. However, DiLEP has less perioperative bleeding and faster recovery than PKRP.
【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R699.8

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