糖尿

发布时间：2018-02-22 23:50

本文关键词： 糖尿病高血压肥胖代谢综合征肾细胞癌病理分级　出处：《山东医药》2016年46期 　论文类型：期刊论文

【摘要】：目的探讨代谢综合征(Met S)组分中糖尿病、高血压及肥胖与肾细胞癌(RCC)患者肿瘤直径及组织学分级的关系。方法回顾性分析362例原发性RCC患者的资料,根据血糖水平及病史,将患者分为糖尿病146例、非糖尿病216例两个水平;根据血压水平,将患者分为高血压202例、非高血压160例两个水平;根据BMI,将患者分为肥胖157例、非肥胖205例两个水平;根据是否同时伴有糖尿病、高血压及肥胖,将患者分为代谢异常者95例、非代谢异常者267例两个水平。对有无糖尿病、高血压、肥胖及代谢异常者与RCC肿瘤直径、组织学分级的关系进行分析。结果代谢异常者RCC肿瘤直径、Fuhrman分级均高于非代谢异常者(P均0.01)。合并糖尿病、高血压及肥胖者RCC的肿瘤直径、Fuhrman分级均较不合并各相应Met S组分者高(P均0.05)。结论合并代谢异常的RCC患者肿瘤直径较大、组织学分级较高。糖尿病、高血压及肥胖均可增加RCC的肿瘤直径与组织学分级。
[Abstract]:Objective to investigate the relationship between diabetes mellitus, hypertension and obesity and tumor diameter and histological grade in patients with renal cell carcinoma (RCC). Methods the data of 362 patients with primary RCC were retrospectively analyzed. The patients were divided into two levels: 146 cases of diabetes mellitus and 216 cases of non-diabetes, 202 cases of hypertension and 160 cases of non-hypertension according to blood pressure level, 157 cases of obesity and 205 cases of non-obesity according to BMI. According to whether diabetes, hypertension and obesity were associated with diabetes, the patients were divided into two levels: 95 patients with abnormal metabolism and 267 patients with non-metabolic abnormality. Results the diameter of RCC tumor in patients with abnormal metabolism was higher than that in patients without abnormal metabolism (P < 0.01). The tumor diameter of RCC patients with hypertension and obesity was higher than that of those without corresponding Met S components (P < 0.05). Conclusion the tumor diameter and histological grade of RCC patients with metabolic abnormalities are larger and higher than those of patients with diabetes mellitus. Hypertension and obesity can increase the tumor diameter and histological grade of RCC.
【作者单位】：天津医科大学第二医院;天津市泌尿外科研究所;
【分类号】：R737.11

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