泌尿系结石患者发病危险因素调查研究

发布时间：2018-02-27 16:19

本文关键词： 泌尿系统结石高脂血症肥胖 Apo E　出处：《河北医学》2016年03期 　论文类型：期刊论文

【摘要】：目的:分析泌尿系统结石患者相关的影响因素,为疾病预防、临床诊断和治疗提供依据。方法:选择2013年1月至2014年1月收治的78例泌尿系统结石患者作为研究组,同时期进行健康体检的健康者44例作为对照组,所有受试者行彩色多普勒超声检查,并检测血钙(Ca)、磷(P)、总胆固醇(TG)、载脂蛋白A(Apo A)、载脂蛋白E(Apo E)、低密度脂蛋白胆固醇(LDL-C),应用Logistic回归法对泌尿系统结石形成的危险因素进行统计分析。结果:与对照组相比,研究组血清中的Ca、TG、Apo E浓度明显偏高,组间差异均有统计学意义(P0.05),而两组之间的血清P、Apo A及LDL-C浓度差异均无统计学意义(P0.05)。Logistic回归分析显示高脂血症、体质指数BMI、家族泌尿系统结石病是其危险因素OR值和95%CI分别为1.524(1.215,1.651),1.315(1.141,1.462)和2.189(1.698,2.054)。结论:泌尿系统结石患者多有血脂代谢及钙代谢异常,高脂血症、肥胖、家族病史是泌尿系统结石形成的危险因素。
[Abstract]:Objective: to analyze the related factors of urinary calculi in order to provide evidence for disease prevention, clinical diagnosis and treatment. Methods: 78 patients with urolithiasis from January 2013 to January 2014 were selected as study group. In the same period, 44 healthy subjects were taken as control group, and all subjects were examined by color Doppler ultrasound (CDFI). The risk factors of urinary system stone formation were analyzed by Logistic regression method, and the results showed that the risk factors of urinary stone formation were analyzed by Logistic regression method, and the results showed that the risk factors of urinary calculi were analyzed by using Logistic regression, and the results were as follows: compared with the control group, the risk factors of urinary calculi were analyzed by using Logistic regression method, apolipoprotein apolipoprotein (apo), apolipoprotein (apo) and low density lipoprotein cholesterol (LDL-C) were detected. In the study group, the serum levels of CaTGG ApoE were significantly higher, and the differences between the two groups were statistically significant (P 0.05). However, there was no significant difference in the serum levels of LDL-C and P0. 05 in the study group. Logistic regression analysis showed that there was hyperlipidemia in the two groups, and there was no significant difference between the two groups. Body mass index (BMI), OR value and 95 CI of family urinary system lithiasis were 1.5241.2151.651and 1.3151.141 / 1.462respectively. Conclusion: urinary system stone patients have abnormal metabolism of blood lipids and calcium, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, obesity, hyperlipidemia, hyperlipidemia, obesity, and hyperlipidemia. Family history is a risk factor for the formation of urinary calculi.
【作者单位】：重庆市石柱县人民医院超声科;
【基金】：重庆市卫计委科研面上项目,(编号:20142166)
【分类号】：R691.4

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