肾脏硬化性上皮样纤维肉瘤1例并文献复习

发布时间：2018-03-05 13:40

本文选题：肾脏肿瘤　切入点：纤维肉瘤　出处：《临床与实验病理学杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的探讨肾脏硬化性上皮样纤维肉瘤(sclerosing epithelioid fibrosarcom,SEF)的临床病理学特征、诊断及鉴别诊断。方法采用HE和免疫组化SP法染色检测1例原发于肾脏SEF的临床病理学特征,并复习相关文献。结果患者男性,CT检查发现右肾占位,大小41 mm×47 mm×39mm,呈混杂密度,内见斑片状高密度影,CT值68 HU。增强CT示:右肾占位轻度强化,右肾乏血供占位。MRI检查:右侧肾脏占位,不典型肾癌待排。病理检查肿块位于右肾中极。镜检:肿瘤细胞呈片状、条索状分布,其间有较多硬化的胶原纤维。免疫表型:vimentin阳性,CK20、CD10个别弱阳性,CK(AE1/AE3)、EMA、CK7、CK19、CK4βE12、CK8/18、p53、S-100、desmin、SMA、RCC、Syn、CgA、PS04s、HMB45、Melan-A、CD34、p63、Pax-8、GATA3均阴性。结论肾脏SEF临床罕见,诊断主要为排他性诊断,鉴别诊断是重点。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis and differential diagnosis of sclerosing epithelioid fibrosarcoma SEF.Methods the clinicopathological features of a case of primary renal SEF were detected by HE and SP immunohistochemical staining. Results the size of the right kidney was 41 mm 脳 47 mm 脳 39 mm, and the CT value was 68 Hu. The contrast enhanced CT showed that the right renal mass was slightly enhanced, and the size was 41 mm 脳 47 mm 脳 39 mm. MRI examination: right kidney occupied, atypical renal carcinoma was to be discharged. Pathological examination showed that the tumor was located in the middle pole of the right kidney. There were more hardened collagen fibers. The immunophenotype was vimentin positive and CK20 CD10 was negative. Conclusion the diagnosis of renal SEF is rare, the diagnosis is mainly exclusive, and the differential diagnosis is the most important.
【作者单位】：安徽省芜湖市第一人民医院病理科;安徽省芜湖市第一人民医院泌尿外科;上海交通大学附属瑞金医院病理科;
【分类号】：R737.11

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