磁共振结合经直肠超声在各PSA区间对前列腺癌的诊断价值

发布时间：2018-03-07 09:46

本文选题：前列腺特异性抗原　切入点：磁共振成像　出处：《中山大学学报(医学科学版)》2017年01期 　论文类型：期刊论文

【摘要】：【目的】探讨磁共振(MRI)结合经直肠超声(TRUS)在不同前列腺特异性抗原(PSA)区间对前列腺癌的诊断价值。【方法】搜集2014年11月至2016年6月在我院的278例患者的临床资料。纳入研究的病例穿刺前均进行了PSA血清学检查,MRI以及TRUS的影像学检查。278例患者分别按PSA水平4~10 ng/m L、10~20 ng/m L、大于20 ng/m L分为A、B、C3组。对3组的MRI结合TRUS的诊断率进行了回顾性分析。【结果】A组MRI+TRUS与TRUS的ROC面积分别为0.73和0.59(P=0.02);B组MRI+TRUS与TRUS的ROC面积分别为0.68和0.56(P0.001);C组MRI+TRUS与TRUS的ROC面积分别为0.74和0.63(P0.001)。B、C两组具有更显著的统计学差异。【结论】MRI结合TRUS在不同PSA水平对前列腺癌的诊断效能均优于单纯的TRUS,表明MRI结合TRUS是提高前列腺癌穿刺检出率的有效方案。
[Abstract]:[objective] to investigate the diagnostic value of MRI combined with transrectal ultrasound trust (TUS) in the diagnosis of prostate cancer in different prostate specific antigen (PSA) regions. [methods] Clinical data of 278 patients with prostate cancer from November 2014 to June 2016 in our hospital were collected. All the patients included in the study underwent PSA serological examination and TRUS imaging examination before puncture. 278 patients were divided into three groups according to the PSA level of 4 ~ 10 ng/m / L ~ 1020 ng/m / L, > 20 ng/m / L respectively. The diagnostic rate of MRI combined with TRUS in the three groups was compared with that in the control group. [WT5 "HZ] [WT5" HZ] [WT5 "BZ] [WT5" BZ] [WT5BZ]. [results] the ROC areas of MRI TRUS and TRUS in group A were 0.73 and 0.59, respectively. The ROC areas of MRI TRUS and TRUS in group B were 0.68 and 0.56, respectively. The ROC areas of MRI TRUS and TRUS in group C were 0.74 and 0.63, respectively. MRI combined with TRUS is superior to trust in the diagnosis of prostate cancer at different PSA levels, which indicates that MRI combined with TRUS is an effective method to improve the detection rate of prostate cancer.
【作者单位】：中山大学附属第一医院泌尿外科;中山大学附属第一医院东院泌尿外科;
【基金】：国家自然科学基金(81001146) 广东省科技计划项目(2012B031800033)
【分类号】：R737.25

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