腹腔镜Sandwich法尿道及周围组织重建改善高风险组前列腺癌根治术后早期尿控的研究

发布时间：2018-03-18 11:07

本文选题：腹腔镜　切入点：Sandwich法尿道及周围组织重建　出处：《首都医科大学学报》2016年03期 　论文类型：期刊论文

【摘要】：目的探讨腹腔镜Sandwich法尿道及周围组织重建技术对高风险组前列腺癌根治术后早期尿控的疗效。方法纳入2011年1月至2015年9月于本院治疗的高风险前列腺癌患者71例,采用腹腔镜Sandwich法尿道及周围组织重建技术47例,采用单纯尿道吻合技术24例,对比两组患者年龄、体质量指数、前列腺体积、术前前列腺特异性抗原(prostate specific antigen,PSA)、临床分期、手术时间、术后引流管拔除时间、术后尿管拔除时间、病理分期、Gleason评分、术后切缘阳性率、淋巴结阳性率及拔除尿管后第2、4、12、24、52周尿控恢复情况。结果两组患者间年龄、体质量指数、前列腺体积、术前PSA、临床分期、病理分期、Gleason评分、术后切缘阳性率、淋巴结阳性率、术后引流管拔除时间的差异均无统计学意义(P0.05);Sandwich法尿道及周围组织重建组手术时间长于对照组(P=0.024)、术后尿管拔除时间显著早于对照组(P0.001),拔除尿管第12周尿控恢复显著优于对照组(P=0.023)。结论腹腔镜Sandwich法尿道及周围组织重建技术安全可行,显著改善高风险组前列腺癌根治术后早期尿控。
[Abstract]:Objective to investigate the effect of laparoscopic Sandwich urethral and peripheral tissue reconstruction on early urinary control after radical resection of prostate cancer in high risk group. Methods 71 patients with high risk prostate cancer who were treated in our hospital from January 2011 to September 2015 were included in this study. Laparoscopic Sandwich technique was used in 47 cases of urethral and peripheral tissue reconstruction, and simple urethral anastomosis was performed in 24 cases. The age, body mass index, prostate volume, specific antigen-PSAs and clinical stages were compared between the two groups. Time of operation, time of extubation of drainage tube, time of extubation, Gleason score of pathological stage, positive rate of incision margin, positive rate of lymph node and recovery of urinary control at 2 ~ (th) ~ (th) ~ (th) ~ (th) ~ (th) ~ (th) ~ (24) ~ (th) week after extubation of urethral catheter. Body mass index (BMI), prostate volume, preoperative PSAs, clinical stage, pathological stage and Gleason score, positive rate of incision margin, positive rate of lymph node, There was no significant difference in the time of extubation of drainage tube after operation. The operation time of urethral and surrounding tissue reconstruction group was longer than that of control group. The time of extubation of urinary tube was significantly earlier than that of control group (P 0.001), and the urinary control recovered significantly at the 12th week after extubation. Conclusion Laparoscopic Sandwich method is safe and feasible for urethral and peripheral tissue reconstruction. Significantly improved early urinary control after radical prostatectomy in high risk groups.
【作者单位】：首都医科大学附属北京朝阳医院泌尿外科;
【基金】：北京市卫生系统高层次卫生技术人才(2011-3-014)~~
【分类号】：R737.25

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