锯叶棕果实提取物软胶囊治疗良性前列腺增生的有效性和安全性分析

发布时间：2018-03-19 11:36

本文选题：锯叶棕果实提取物　切入点：良性前列腺增生　出处：《中华男科学杂志》2015年12期 　论文类型：期刊论文

【摘要】：目的:探讨锯叶棕果实提取物软胶囊治疗良性前列腺增生(BPH)的有效性和安全性。方法:采用多中心、开放性临床研究,对临床和实验室确诊的165例BPH患者给予锯叶棕果实提取物软胶囊口服1粒/次(160 mg),1次/d,6周后及12周试验结束时比较患者治疗前后的疗效。主要疗效指标:IPSS评分、前列腺体积、残余尿量;次要疗效指标:尿流率、生活质量评分(QOL)。结果:治疗6周后,患者的国际前列腺症状评分(IPSS)和QOL较前有所改善,治疗12周后,患者的IPSS评分、QOL评分、尿流率、残余尿较治疗前均有明显改善。研究过程中有1例不良事件发生。结论:锯叶棕果实提取物软胶囊治疗BPH是有效和安全的。
[Abstract]:Objective: to investigate the efficacy and safety of soft capsule of sawleaf palm fruit extract in the treatment of benign prostatic hyperplasia (BPH). A total of 165 patients with BPH were given a soft capsule of sawleaf palm fruit extract once a day after 6 weeks and 12 weeks to compare the curative effect before and after treatment. The main outcome measures were: 1% IPSs score, prostate volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, prostatic volume, and prostatic volume. Residual urine volume; secondary outcome measures: urinary flow rate, quality of life score and QOL.Results: after 6 weeks of treatment, the international prostatic symptom score (IPSS) and QOL were improved. After 12 weeks of treatment, the IPSS score, QOL score and urinary flow rate of the patients were improved. Residual urine was significantly improved compared with that before treatment. One case of adverse events occurred in the course of the study. Conclusion: soft capsule of sawleaf palm fruit extract is effective and safe in the treatment of BPH.
【作者单位】：南京医科大学第一附属医院泌尿外科;江苏省中医院泌尿外科;南京军区南京总医院泌尿外科;南京医科大学第二附属医院泌尿外科;南京医科大学附属无锡人民医院泌尿外科;张家港市第一人民医院泌尿外科;宜兴市人民医院泌尿外科;苏州大学附属第三医院/常州市第一人民医院泌尿外科;江阴市中医院泌尿外科;扬州大学第四临床医学院/南通瑞慈医院泌尿外科;南通大学附属泰州市人民医院泌尿外科;盐城市第一人民医院泌尿外科;苏州大学附属第二医院泌尿外科;
【分类号】：R697.32

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