后腹腔镜与输尿管镜技术治疗感染性输尿管上段结石患者后对其肾功能及其相关指标的影响

发布时间：2018-03-20 05:34

本文选题：后腹腔镜　切入点：输尿管镜技术　出处：《中华医院感染学杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的研究后腹腔镜与输尿管镜技术治疗感染性输尿管上段结石者后对其肾功能及C-反应蛋白(CRP)、白介素-6(IL-6)、白细胞计数(WBC)的影响,以期为感染性输尿管上段结石的治疗提供数据依据。方法收集2014年1月-2015年12月医院经输尿管内碎石技术(URSL)及腹腔镜输尿管切开取石术(RPLU)治疗感染性输尿管上段结石患者的临床资料;采用URSL治疗124例,为URSL组,采用RPLU治疗94例,为RPLU组,对比分析两组患者的临床资料、肾功能指标、炎症指标、术后并发症及术后结石清除情况。结果两组患者手术前BUN、SCr、NGAL及CRP、IL-6、WBC对比,差异无统计学意义,URSL组患者术后NGAL水平高于同组治疗前及RPLU组同期(P0.05),RPLU组患者术后1dCRP、IL-6水平高于同组术前及URSL组同期(P0.05),术后7dCRP、IL-6及WBC水平低于同组术前(P0.05);两组术后并发症比较,差异无统计学意义,两组30d治疗效果均为100.00%,差异无统计学意义。结论后腹腔镜与输尿管镜技术均可有效治疗感染性输尿管上段结石,两种术式各有利弊,应结合临床选择术式。
[Abstract]:Objective to study the effects of retroperitoneal laparoscopy and ureteroscopy on renal function, C-reactive protein (CRP), interleukin-6 (IL-6) and white blood cell count (WBC) in patients with upper ureteral calculi. Methods from January 2014 to December 2015, hospital transureteral lithotripsy (URSL) and laparoscopic ureterolithotomy (RPLU) were collected for the treatment of infectious upper ureteral calculi. Clinical data of stone patients; 124 cases were treated with URSL, URSL group, 94 cases were treated with RPLU, and 94 cases were treated with RPLU. The clinical data, renal function index and inflammation index of the two groups were compared and analyzed. Results before operation, the patients in the two groups were compared with BUN-SCrNGAL and CRPIL-6 WBC. There was no significant difference in postoperative NGAL levels between the two groups. The level of NGAL was significantly higher in Url group than that in the same group before treatment and 1 day after operation in RPLU group. The level of IL-6 and WBC in URSL group was higher than that in the same group and URSL group at 1 day after operation, and the levels of IL-6 and WBC in URSL group were lower than those in the same group at 7 days after operation (P 0.05), and the postoperative complications were compared between the two groups. There was no significant difference between the two groups in 30 days treatment, the difference was not statistically significant. Conclusion retroperitoneal laparoscopy and ureteroscopy are effective in the treatment of infectious upper ureteral calculi, both of which have advantages and disadvantages, and should be combined with clinical choice.
【作者单位】：南阳市中心医院泌尿外科;南阳医学高等专科学校;
【基金】：河南省卫生计生委科技攻关项目(201405011)
【分类号】：R699.4

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