超声造影和磁共振增强在前列腺癌诊断中价值分析

发布时间：2018-03-21 05:32

  本文选题：前列腺癌　切入点：超声造影　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨前列腺超声造影(Contrast-enhance ultrasound CEUS)、磁共振(Magnetic resonance imaging MRI)增强及其联合成像在不同前列腺特异性抗原(Prostate sPecific antigen PSA)区间前列腺癌(Prostatic cancer PCa)诊断中的临床应用价值。方法:回顾性分析132例疑似前列腺癌患者,均行CEUS、MRI增强检查,并进一步经直肠前列腺穿刺活检术证实,结合病理结果比较分析两种诊断方法及其联合成像在前列腺癌诊断中临床应用价值。结果:CEUS、MRI增强及二者联合应用对前列腺癌诊断的灵敏度分别为75.43%、80.70%、92.98%,特异度分别为77.33%、86.67%、73.33%,二者联合诊断的灵敏度高于CEUS、MRI增强单独一种技术,差异均具有统计学意义(P0.05),MRI增强诊断的特异度高于联合诊断,差异有统计学意义(P0.05)。患者在4PSA≤10ng/ml范围内,CEUS、MRI增强及二者联合应用特异度分别为82.00%、96.00%、80.00%,MRI增强诊断特异度高于CEUS及二者联合应用,差异均有统计学意义(P0.05)。在10PSA≤20ng/ml范围内,CEUS、MRI增强及二者联合应用对前列腺癌诊断的灵敏度分别为42.86%、52.38%、80.95%,特异度分别为73.68%、68.42%、63.16%,二者联合应用诊断的灵敏度高于CEUS、MRI增强单独一种技术,差异均具有统计学意义(P0.05)。在PSA20ng/ml中,三种方法均诊断正确。结论:CEUS与MRI增强对前列腺癌诊断各有优势,二者联合诊断可以提高灵敏度,优于单独一种诊断方法。同时MRI增强对前列腺癌诊断的特异度优于联合诊断方法。在4PSA≤10ng/ml区间,MRI增强具有较高的诊断特异性,有诊断优势;10PSA≤20ng/ml中,CEUS和MRI增强联合应用具有较高的灵敏度,具有诊断优势;在PSA20ng/ml中CEUS检查简便,可提高前列腺穿刺活检定位准确性,具有诊断优势。
[Abstract]:Objective: to evaluate the clinical value of contrast-enhanced ultrasound ultrasound enhanced Mr magnetic resonance imaging MRI and its combined imaging in the diagnosis of prostatic cancer PCA with different prostate sPecific antigen PSAs. Methods: a retrospective review was made. Sex analysis of 132 suspected prostate cancer patients, All patients were examined by CEUSUS MRI and confirmed by transrectal prostatic biopsy. The clinical value of two diagnostic methods and their combined imaging in the diagnosis of prostate cancer was compared with pathological results. Results the sensitivity of enhanced MRI and combined use of the two methods in the diagnosis of prostate cancer was 75.4343 and 80.70, respectively. The specificity of the two methods was 75.4343 and 80.70, respectively. The specificity of the two methods was 75.4343 and 80.70, respectively. The sensitivity of the combined diagnosis of the two is higher than that of the CEUST MRI enhanced by a single technique, 77.33 / 86.67 / 73.33 / 77.33 / 77.33 / 86.67 / 73.33, respectively. The difference was statistically significant. The specificity of enhanced MRI was higher than that of combined diagnosis. In the range of 4PSA 鈮，

本文编号：1642462