天津地区泌尿系结石成分分析

发布时间：2018-03-21 08:40

本文选题：泌尿系结石　切入点：结石分析　出处：《医学理论与实践》2013年05期 　论文类型：期刊论文

【摘要】：目的:了解天津地区泌尿系结石化学成分构成。比较上下尿路结石成分的特点,年龄、性别构成比例及城市居住人群与郊区居住人群的尿路结石成分的异同,为泌尿系结石的治疗及预防提供参考。方法:收集天津医科大学第二医院2005年1月-2009年12月门诊体外冲击波碎石后排出和住院患者手术取出的泌尿系结石标本420例,使用红外光谱法进行定量和定性分析。结果:420例泌尿系结石中单纯草酸钙结石占26.4%(111/420),草酸钙+磷酸钙结石占31.4%(132/420),草酸钙+羟基磷灰石结石占17.4%(73/420),尿酸结石占12.4%(52/420),碳酸磷灰石结石占8.8%(37/420),磷酸镁铵结石占3.1%(13/420),胱氨酸结石占0.5%(2/420),磷酸氢钙结石为0,其中含钙结石占75.2%(316/420);尿酸结石比例高于国内文献报道;男女患病比例为2.75∶1,发病高峰在25～65岁之间,老年泌尿系结石的发病率有增加的趋势;上尿路结石占94.5%(397/420),下尿路结石占5.5%(23/420),比例为17.3∶1;郊区下尿路结石所占比例9.0%(12/134)高于市区3.8%(11/286),结石成分无明显差异;5年间结石成分无明显差异。结论:(1)本组含钙结石上尿路比下尿路多,含尿酸结石及磷酸镁铵结石下尿路比上尿路多。(2)尿酸结石所占结石总数百分比高于国内外文献报道。这对于本地区治疗及预防尿石有一定的参考价值。(3)泌尿系结石发病年龄高峰延迟,说明老年泌尿系结石的发病率增加。(4)郊区下尿路结石比例高于市区,考虑与生活条件及医疗水平有关。(5)本地区5年内结石成分构成无明显变化。
[Abstract]:Objective: to understand the chemical composition of urinary calculi in Tianjin area. To compare the characteristics, age, sex ratio of upper and lower urinary calculi, and the similarities and differences of urinary calculi between urban and suburban residents. Methods: 420 specimens of urinary calculi were collected from outpatients of Tianjin Medical University from January 2005 to December 2009 after extracorporeal shock wave lithotripsy (ESWL) and surgical removal from inpatients. Results among 420 cases of urinary calculi, calcium oxalate stone accounted for 26.4% / 420%, calcium oxalate calcium phosphate stone accounted for 31.42% 420%, calcium oxalate hydroxyapatite stone accounted for 17.4% 73 / 420%, uric acid stone accounted for 12.42% 420%, phosphate carbonate ash accounted for 12.422% 420U, calcium oxalate hydroxyapatite stone accounted for 17.473 / 420 stone, uric acid stone accounted for 12.42P / 420g, calcium oxalate calcium phosphate stone accounted for 31.4% 420g. The proportion of calcium stone in calcium phosphate stone was 0, the calcium stone in calcium phosphate stone was 75.22% in calcium phosphate stone, the proportion of uric acid stone was higher than that in domestic literature, the proportion of uric acid stone was higher than that in domestic literature. The ratio of calcium stone to calcium phosphate stone was 3 16% 420%, and the proportion of uric acid stone was higher than that of domestic literature, and the ratio of calcium stone to calcium stone was 3 16% 4 20%, and the proportion of uric acid stone was higher than that of domestic literature. The ratio of male to female was 2.75: 1, the peak of the disease was between 25 and 65 years old, and the incidence of urinary calculi in the elderly had an increasing trend. The ratio of upper urinary calculi to upper urinary calculi was 94.5- 397 / 420g, lower urinary calculi accounted for 5.5w / 420g, the proportion was 17.3: 1; the proportion of lower urinary calculi in suburban areas was 9.012 / 134), which was higher than that in urban areas (3.811 / 286g), and there was no significant difference in stone composition in 5 years. Conclusion: the calcium calculus in upper urinary tract is more than that in lower urinary tract. The percentage of total calculi in the lower urinary tract with uric acid stone and ammonium magnesium phosphate stone is higher than that in the upper urinary tract, which is higher than that reported in domestic and foreign literature. This is of certain reference value for the treatment and prevention of urolithiasis in this area. The peak age of stone onset was delayed, The results showed that the incidence of urinary calculi in the elderly increased. 4) the proportion of lower urinary calculi in the suburbs was higher than that in the urban areas, considering that there was no significant change in the composition of stones in this area within 5 years, which was related to the living conditions and the medical level.
【作者单位】：天津市宝坻区人民医院泌尿外科;天津医科大学第二医院泌尿外科;
【分类号】：R691.4

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