系统评价经尿道铥激光前列腺剜除术的安全性与有效性

发布时间：2018-04-06 02:30

  本文选题：铥激光前列腺剜除术　切入点：经尿道前列腺电切术　出处：《激光杂志》2013年03期

【摘要】：目的:比较经尿道铥激光前列腺剜除术(TmLEP)与经尿道前列腺电切术(TURP)治疗良性前列腺增生症的安全性及有效性。方法:计算机检索CochraneLibrary、PubMed、EMbase、维普、万方及CNKI等在线数据库,收集比较TmLEP和TURP治疗良性前列腺增生症的随机对照试验(RCT)及病例对照试验(CCT)。经筛选、资料提取和质量评价后,采用RevMan 5.1软件进行Meta分析。结果:共纳入5个研究,554例患者。Meta分析结果显示:①在安全性方面:与TURP相比,TmLEP术中出血量较少〔WMD-7.07,CI(-8.99,-5.16)P0.00001〕、血清钠盐降低量少〔WMD-3.07,95%CI(-4.36,-1.78)P0.00001〕、输血人数比例低〔RR 0.10,CI(0.02,0.42)P=0.002〕、术后留置导尿时间较短〔WMD-0.92,95%CI(-1.11,-0.73)P0.00001〕、住院天数较短〔WMD-1.82,95%CI(-3.36,-0.28)P=0.02〕,手术时间及术后并发症差异无统计学意义(P0.05);②在有效性性方面:术后1月TmLEP的最大尿流率(Qmax)评分高于TURP〔WMD-1.37,95%CI(-2.20,-0.53)P=0.01〕,术后6、12月残余尿量(PVR)的改善TmLEP优于TURP。其它组间指标差异均无统计学意义(P0.05)。结论:TmLEP与TURP对BPH有相似的疗效。TmLEP术中出血量较少、血清钠盐降低量少、输血人数少、术后留置导尿时间较短、住院天数较短。
[Abstract]:Objective: to compare the safety and efficacy of TmLEP and TURP in the treatment of benign prostatic hyperplasia.Methods: the online databases of Cochrane Library PubMedbase, Wiper, Wanfang and CNKI were searched, and the randomized controlled trials of TmLEP and TURP in the treatment of benign prostatic hyperplasia were compared with those in the case control trial.After screening, data extraction and quality evaluation, Meta analysis was carried out with RevMan 5.1 software.鏈�鍚庣暀缃�瀵煎翱鏃堕棿杈冪煭銆擶MD-0.92,95%CI(-1.11,-0.73)P0.00001銆，

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