左卡尼汀口服液联合黄地助育汤治疗少弱精症男性不育的临床研究

发布时间：2018-04-14 09:05

本文选题：左卡尼汀口服液 + 黄地助育汤　；参考：《中华中医药学刊》2017年11期

【摘要】：目的:观察左卡尼汀口服液联合黄地助育汤治疗少弱精症男性不育的临床疗效。方法:对临床上符合少、弱精症诊断的120例男性不育患者随机分为两组,其中治疗组62例应用左卡尼汀口服液加黄地助育汤进行治疗,对照组58例单纯给予黄地助育汤治疗,两组均以3个月为1个疗程。疗程结束后观察两组精液量、精子浓度、精子活力(a级和b级)及精子存活率的变化并判断疗效。结果:治疗后两组患者精子浓度、精子活力(a级和b级)及精子存活率均较治疗前有明显改善(P0.05,P0.01);治疗组对精子存活率和a级精子比率的改善优于对照组(P0.05);治疗组总有效率为87.1%,对照组总有效率为72.4%,差异具有显著性(P0.05)。两组在治疗过程中未发生不良事件。结论:运用左卡尼汀口服液联合黄地助育汤治疗少弱精症男性不育,疗效可靠且不良反应少,值得临床推广。
[Abstract]:Objective: to observe the clinical effect of Zuocanitine oral liquid combined with Huangdi Zhuyu decoction on male infertility with oligospermia.Methods: one hundred and twenty male infertile patients with weak spermatosis were randomly divided into two groups: the treatment group (62 cases) was treated with Zuo Carnitine oral liquid plus Huangdi Zhuyu decoction, and the control group (58 cases) was treated with Huangdi Zhuyu decoction.Both groups were treated with 3 months as a course of treatment.After the course of treatment, the changes of spermatozoa volume, sperm concentration, sperm motility and sperm viability were observed and the therapeutic effect was evaluated.Results: after treatment, the sperm concentration of the two groups,The sperm motility grade A and B) and spermatozoa survival rate of the treatment group were significantly improved than that of the control group, the sperm survival rate of the treatment group was better than that of the control group, the total effective rate of the treatment group was 87.1%, the total effective rate of the control group was 72.4%, and that of the control group was 72.4%, the total effective rate of the treatment group was higher than that of the control group.The difference was significant (P 0.05).There were no adverse events in both groups.Conclusion: Zuo Carnitine oral liquid combined with Huangdi Zhuyu decoction in the treatment of male infertility with oligozoospermia has a reliable curative effect and few adverse reactions, so it is worth popularizing in clinic.
【作者单位】：云南省中医医院/云南中医学院第一附属医院泌尿男科;浙江中医药大学第二临床医学院;
【基金】：国家自然科学基金项目(81260540)
【分类号】：R698.2

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