夫妻活体供肾移植临床疗效对比及其现状分析

发布时间：2018-04-14 10:40

本文选题：夫妻 + 活体肾移植　；参考：《实用医学杂志》2017年01期

【摘要】：目的:研究夫妻肾移植所具有的临床效果,分析亲属活体肾移植的现状及其影响因素和家庭、社会意义。方法:回顾性收集郑州大学第一附属医院肾移植科自2011年1月至2013年12月所有夫妻肾移植病例资料,排除供肾影响因素,选取同期供肾为女性、供受者年龄接近的具有血缘关系的亲属活体肾移植兄弟姐妹组,收集两组受者术后恢复情况,统计学方法对比两组肾功能恢复有无差异。结合当今社会现状,在供肾尤其短缺的情况下,分析夫妻活体肾移植所具有的临床、社会及家庭意义。结果:夫妻组12例、兄弟姐妹组8例,供受者年龄相差分别为(0.33±0.98)岁、(2.29±7.23)岁,人主要组织相容性抗原配合:夫妻组配合均小于3个,兄弟姐妹组均大于或等于3个。两组受者血肌酐、尿素氮下降趋势差异均无统计学意义(P=0.84、P=0.79)。结论:夫妻供肾在供肾质量、器官来源上具有明显的优势,而且具有较好的临床疗效和较大的社会、家庭意义。
[Abstract]:Objective: to study the clinical effect of husband and wife kidney transplantation, and to analyze the present situation, influencing factors, family and social significance of relative living donor kidney transplantation.Methods: from January 2011 to December 2013, all cases of renal transplantation from husband and wife in the Department of Renal Transplantation, first affiliated Hospital of Zhengzhou University, were collected retrospectively, and the influencing factors of donor kidney were excluded, and the donor kidney was selected as female in the same period.The patients in the sibling group were collected and the recovery of renal function in the two groups was compared with that of the two groups by statistical method.The clinical, social and family significance of living donor kidney transplantation was analyzed under the condition of shortage of donor kidney.Results: there were 12 cases of husband and wife group and 8 cases of sibling group. The age difference of donor was 0.33 卤0.98 years old and 2.29 卤7.23 years old, respectively. The cooperation of human main histocompatibility antigen was less than 3 in husband and wife group, and greater than or equal to 3 in brother and sister group.There was no significant difference in blood creatinine and urea nitrogen between the two groups.Conclusion: the donor kidney of husband and wife has obvious advantages in the quality of donor kidney and organ source, and has better clinical curative effect and greater social and family significance.
【作者单位】：郑州大学第一附属医院肾移植科;郑州大学基础医学院;
【基金】：郑州大学第一附属医院青年基金(编号:2011-QN010) 郑州大学大学生创新训练项目(编号:2015xjxm291)
【分类号】：R699.2

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