急性左心衰竭患者发生I型心肾综合征的相关危险因素分析

发布时间：2018-04-19 16:05

本文选题：I型心肾综合征 + 急性左心衰竭　；参考：《中国现代医学杂志》2017年25期

【摘要】：目的探讨急性左心衰竭患者发生I型心肾综合征(I型CRS)的相关危险因素。方法选取2012年5月-2015年5月就诊于郑州大学第一附属医院心内科、肾内科、急诊科的176例急性左心衰竭患者为研究对象。依据是否发生I型CRS将患者分为研究组(I型CRS组)和对照组(非I型CRS组)。回顾性分析两组患者临床、生化检查及原发病史资料,并运用多因素Logistic回归模型对急性心力衰竭患者发生I型CRS的相关危险因素进行分析。结果急性左心衰竭患者I型CRS发生率为31.81%。年龄、血红蛋白(HGB)、脑钠肽(BNP)、尿素氮(BUN)、肌酐(Scr)、尿酸(UA)、肾小球滤过率(MDRD-e GFR),扩张型心脏病、高血压、糖尿病,以及使用利尿剂、ACRI/ARB和血管活性药物在研究组和对照组间比较差异有统计学意义(均P0.05)。经Logistic多因素回归分析校正其他因素后发现,MDRD-e GFR60 ml/min、贫血、高血压、糖尿病、使用利尿剂和血管活性药物为急性左心衰竭患者发生I型CRS的危险因素,其风险比(OR)值分别为3.79、8.54、5.02、2.65、3.45和1.99。结论入院时MDR D-e GFR60 ml/min和贫血是急性心力衰竭患者发生I型CR S的危险因素;高血压、糖尿病、利尿剂和血管活性药物应用可增加其发病的风险。
[Abstract]:Objective to explore the related risk factors of type I cardionrenal syndrome (type I CRS) in patients with acute left heart failure. Methods 176 patients with acute left heart failure in the Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, the Department of Nephrology and emergency department, in May, May 2012, were selected to be divided into the study group (I type C) according to the occurrence of I CRS. RS group and control group (non I type CRS). Retrospective analysis of two groups of patients with clinical, biochemical and primary history, and the use of multiple factor Logistic regression model to analyze the risk factors associated with I type CRS in patients with acute heart failure. Results the incidence of I type CRS in patients with acute left heart failure is 31.81%. age, hemoglobin (HGB), brain Natriuretic peptide (BNP), urea nitrogen (BUN), creatinine (Scr), uric acid (UA), glomerular filtration rate (MDRD-e GFR), dilated heart disease, hypertension, diabetes, and the use of diuretic, ACRI/ARB, and vasoactive drugs between the study group and the control group were significant (P0.05) in the study group and the control group. After the Logistic multivariate regression analysis corrected the other factors, MDRD-e GFR60 ml/min, anemia, hypertension, diabetes, the use of diuretics and vasoactive drugs as a risk factor for I type CRS in patients with acute left heart failure, the risk ratio (OR) values are 3.79,8.54,5.02,2.65,3.45 and 1.99. conclusion, MDR D-e GFR60 ml/min and poor blood are the risk factors for acute heart failure patients Hypertension, diabetes, diuretics and vasoactive drugs can increase the risk of the disease.

【作者单位】：郑州大学第一附属医院心内科;
【分类号】：R541;R692

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