经尿道等离子切除与传统电切术治疗膀胱肿瘤的meta分析

发布时间：2018-04-30 10:36

本文选题：等离子切除 + 膀胱肿瘤　；参考：《重庆医科大学》2014年硕士论文

【摘要】：目的研究与传统电切（TURBT）治疗膀胱肿瘤相比，经尿道等离子切除（PKRBT）在临床使用中的优点和缺点，为以后临床决策及研究提供客观的依据。方法通过计算机检索1993年-2013年Pubmed、EMbase、Cochrane图书馆、CNKI、中国生物医学文献数据库、维普数据库等，通过手工检索辅助完整的收集相关文献，搜索内容为所有涉及比较经尿道等离子切除与传统电切术处理膀胱肿瘤的随机对照试验，按照纳入与排除标准选择合适文献，通过资料提取和质量评价后其中7篇符合等离子切除术与经尿道电切术的随机对照研究（RCTs），，应用Reman5.0软件进行数据处理和分析。结果对成功纳入的符合标准的7篇文献，统计共有643例患者，进行meta分析后得出结果如下：1.手术时间比较两组无明显差异[WMD=-0.89，95%CI（-2.77，0.99），P=0.35]；2.术中出血量比较两组无明显差异[WMD=-6.79，95%CI（-16.12，2.55），P=0.15]；3.手术并发症比较等离子切除术低于传统经尿道电切术[RR=0.31，95%CI（0.21，0.48），P0.00001]；4.术后复发率等离子切除术低于传统经尿道电切术[RR=0.70，95%CI（0.53，0.92），P0.001]。结论与传统经尿道电切术治疗浅表性膀胱癌相比，经尿道等离子切除术更安全有效，能降低手术并发症及术后2年内的复发率。
[Abstract]:Objective to study the advantages and disadvantages of transurethral resection of PKRBT in the treatment of bladder neoplasms compared with traditional TURBT, and to provide an objective basis for future clinical decision making and research. Methods CNKI, China Biomedical Literature Database and Wiper Database were searched by computer from 1993 to 2013 in the Pubmedus EMbase Cochrane Library. The relevant documents were collected by manual retrieval. All randomized controlled trials involving the comparison of transurethral plasma resection and conventional electroresection of bladder tumors were conducted, and appropriate literature was selected according to the inclusion and exclusion criteria. After data extraction and quality evaluation, seven of them were randomly compared with plasma resection and transurethral resection. The data were processed and analyzed by Reman5.0 software. Results A total of 643 patients were included successfully in 7 articles that met the criteria. The results of meta analysis were as follows: 1. 1. There was no significant difference in operation time between the two groups. There was no significant difference in intraoperative blood loss between the two groups [WMD-6.79N95, CI-16.122.55P0. 15]. Compared with conventional transurethral resection, the complications of operation were lower than that of conventional transurethral resection. The recurrence rate of plasma resection was lower than that of traditional transurethral resection. Conclusion compared with traditional transurethral resection, transurethral plasma resection is more safe and effective in the treatment of superficial bladder cancer, and can reduce the postoperative complications and recurrence rate within 2 years.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.14

【参考文献】