缬沙坦联合肾炎康复片治疗肾小球肾炎蛋白尿的疗效观察

发布时间：2018-05-05 00:33

本文选题：慢性肾小球肾炎 + 蛋白尿　；参考：《中华中医药学刊》2017年08期

【摘要】：目的:探讨和分析采取缬沙坦联合肾炎康复片治疗慢性肾小球肾炎蛋白尿的临床疗效及价值。方法:选取医院2012年1月—2014年1月收治的70例慢性肾小球肾炎蛋白尿患者为研究对象,依据入院日期单双号随机分成对照组和观察组,对照组采取缬沙坦治疗,观察组行缬沙坦治疗基础上,同时给予肾炎康复片治疗,分析和对比治疗前后血肌酐、血清尿素氮、尿蛋白含量的变化情况及临床治疗效果。结果:观察组总有效率为91.43%,明显高于对照组71.43%,治疗3个月后尿蛋白含量明显较对照组降低(P0.05),其他血肌酐、血清尿素氮水平比较差异不大,且两组治疗前3项指标测定结果对比差异不明显(P0.05)。结论:对慢性肾小球肾炎蛋白尿患者采取缬沙坦联合肾炎康复片治疗,能有效减轻蛋白尿症状,治疗效果显著,这对于促进患者肾功能恢复有积极意义,有临床推广价值。
[Abstract]:Objective: to investigate and analyze the clinical effect and value of valsartan combined with nephritis rehabilitation tablet in the treatment of chronic glomerulonephritis proteinuria. Methods: from January 2012 to January 2014, 70 patients with chronic glomerulonephritis proteinuria were randomly divided into two groups: control group and observation group. The control group was treated with valsartan. The observation group was treated with valsartan at the same time. The changes of serum creatinine, serum urea nitrogen, urine protein content and clinical therapeutic effect were analyzed and compared before and after treatment. Results: the total effective rate of the observation group was 91.43, which was significantly higher than that of the control group (71.43). After 3 months of treatment, the urine protein content in the observation group was significantly lower than that in the control group (P 0.05). There was no significant difference in other serum creatinine and serum urea nitrogen levels. There was no significant difference in the results of the three indexes before treatment between the two groups (P 0.05). Conclusion: valsartan combined with nephritis rehabilitation tablets can effectively alleviate the symptoms of proteinuria in patients with chronic glomerulonephritis proteinuria, which has a positive significance for promoting the recovery of renal function in patients with chronic glomerulonephritis.
【作者单位】：河北省中医院肾病科;河北医科大学;天津中医药大学;浙江大学医学院附属儿童医院;
【基金】：河北省中医药管理局项目(2012029)
【分类号】：R692.31

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