2683例IgA肾病患者临床特征与中西药联合应用分析

发布时间：2018-05-08 04:07

本文选题：IgA肾病 + 临床特征　；参考：《中华中医药杂志》2017年03期

【摘要】：目的:研究IgA肾病患者的临床特征与中西药联合应用情况,为优化临床治疗提供依据。方法:选取全国15家三级甲等医院信息管理系统中2 683例IgA肾病住院患者信息进行分析。结果:2 683例IgA肾病住院患者表现为慢性肾小球肾炎者占58.22%,表现为肾功能不全者占25.42%,疾病过程中出现呼吸道感染较为多见,占15.77%。合并疾病中前3位为高血压病(507例,18.90%)、贫血(140例,5.22%)及肾囊肿(77例,2.87%)。西药的使用与KDIGO指南基本一致,中药以虫草菌发酵制剂以及活血化瘀剂使用最为广泛。中西药物联合应用中,虫草菌发酵制剂与泼尼松龙组合使用频率最高;中西药物按类别联合应用中,活血化瘀剂与激素类药联合应用频率最高。结论:治疗IgA肾病时,在西医治疗基础上,应重视补益肺肾剂以及活血化瘀剂的应用。
[Abstract]:Objective: to study the clinical characteristics of patients with IgA nephropathy and the application of traditional Chinese medicine and western medicine in order to provide basis for optimizing clinical treatment. Methods: the information of 2 683 patients with IgA nephropathy in the information management system of 15 Grade 3A hospitals in China were analyzed. Results in the 2 683 cases of IgA nephropathy, chronic glomerulonephritis was found in 58.22 cases, and renal insufficiency in 25.42 cases. Respiratory tract infection was more common in the process of disease, accounting for 15.7777%. The top 3 cases of complicated diseases were 507 cases of hypertension and 18.90%, 140 cases of anemia and 5.22% of anemia) and 77 cases of renal cysts and 77 cases of renal cyst. The use of western medicine is basically consistent with the KDIGO guidelines. Chinese medicine is the most widely used Cordyceps fermentation preparation and blood circulation and blood stasis agent. In the combination of Chinese and western medicine, the combination frequency of fermentation preparation of Cordyceps sinensis and prednisolone was the highest, and the combination of Chinese and western medicine by type was the highest. Conclusion: in the treatment of IgA nephropathy, the application of tonifying lung and kidney and activating blood circulation and removing stasis should be paid more attention to on the basis of western medicine.
【作者单位】：中国中医科学院中医临床基础医学研究所;中国中医科学院西苑医院;中国人民大学统计学院;中国人民解放军海军总医院;
【基金】：中国中医科学院自主选题项目“中药上市后临床再评价关键技术创新团队”(No.PY1303);中国中医科学院基本科研业务费自主选题项目(No.Z0406) 北京市中医药科技发展专项(No.JJ2014-53) 国家自然科学基金青年科学基金项目(No.81403196)~~
【分类号】：R692.31

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