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经皮肾镜超声碎石术在感染性肾结石中的疗效及对患者应激激素的影响观察

发布时间:2018-05-13 17:58

  本文选题:感染性肾结石 + 经皮肾镜超声碎石术 ; 参考:《中华医院感染学杂志》2017年06期


【摘要】:目的观察经皮肾镜超声碎石术治疗对于感染性肾结石中病患应激激素分泌的影响,分析该法的治疗价值。方法选择2013年10月-2015年8月医院进行经皮肾镜超声碎石术治疗的感染性肾结石患者89例为超声组,另选同期气道弹压碎石治疗的89例感染性结石病患为气道弹压组,观察治疗前后两组患者血清应激激素、应激炎性指标的变化,并对比组间疗效和并发症。结果超声组手术时间(69.72±9.58)min、术后住院时间(6.82±1.29)d、术中出血(75.26±15.64)ml明显低于对照组,差异有统计学意义(P0.05);治疗后,超声组血管紧张素-Ⅱ(Ang-Ⅱ)(52.27±3.54)pg/ml、促肾上腺皮质激素(ACTH)(26.17±2.97)pg/ml、去甲肾上腺素(NE)(275.08±23.01)ng/ml、皮质醇(Cor)(171.65±9.54)ng/ml、肾上腺素(AD)(0.23±0.09)ng/ml、降钙素原(PCT)(23.45±0.56)μg/ml、白介素-6(IL-6)(9.52±1.64)pg/ml、超敏C-反应蛋白(hs-CRP)(7.69±1.89)mg/L、一氧化氮(NO)(12.21±1.31)μmol/L明显低于气道弹压组,差异有统计学意义(P0.05);超声组临床疗效(88.76%)明显高于对照组66.29%,差异有统计学意义(P0.05)。结论经皮肾镜超声碎石术治疗感染性肾结石不仅具有较高的取净率、术后恢复快,而且对患者应激指标影响小、手术安全性更高。
[Abstract]:Objective to observe the effect of percutaneous nephrolithotripsy on stress hormone secretion in patients with infectious renal calculi. Methods Eighty-nine patients with infectious renal calculi treated by percutaneous nephrolithotripsy from October 2013 to August 2015 were selected as ultrasound group, and 89 patients with infectious calculi treated with airway elastic lithotripsy at the same time were selected as tracheobronchial pressure group. The changes of serum stress hormone and stress inflammatory index were observed before and after treatment, and the curative effect and complications were compared between the two groups. Results the operation time was 69.72 卤9.58 minutes, the postoperative hospitalization time was 6.82 卤1.29 minutes, and the intraoperative bleeding was 75.26 卤15.64)ml significantly lower than that in the control group (P 0.05). 瓒呭0缁勮绠$揣寮犵礌-鈪,

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