双J管管壁结石形成影响因素的横断面研究

发布时间：2018-05-16 04:25

本文选题：双J管 + 管壁结石　；参考：《四川大学学报(医学版)》2015年03期

【摘要】：目的了解双J管管壁结石形成的基本情况,探讨分析双J管管壁结石形成的影响因素。方法纳入2014年2~7月在我科因上尿路结石接受输尿管软镜联合钬激光碎石术的患者共84例,收集相关临床资料,使用电脑体式显微镜观测双J管管壁结石形成情况,对临床资料与管壁结石形成之间的关系采用t检验、χ2检验、Fisher确切概率法、logistic回归进行统计学分析。结果双J管平均留置时间(17.0±6.0)d,67例(79.8%)双J管形成管壁石膜。石膜形成组较未形成石膜组更年轻〔(44.9±11.5)岁vs.(54.4±12.6)岁,P=0.004〕;尿蛋白阳性患者的管壁石膜形成率更高〔62/73(84.9%)vs.5/11(45.5%),P=0.002〕;尿路感染阳性者较阴性者石膜形成率高〔26/28(92.9%)vs.41/56(73.2%),P=0.035〕;血尿阳性者较阴性者石膜形成率高〔67/80(83.8%)vs.0/4,P=0.001〕。不同性别、双J管留置时间、血清钙、无机磷、尿酸、尿pH、结石类型之间石膜形成率差异无统计学意义(P0.05)。取5例双J管管壁结石进行结石成分分析,发现与原发结石成分完全一致。Logistic回归发现石膜形成与低龄和尿蛋白相关(P0.05),与血尿和尿路感染无关(P0.05)。结论影响管壁石垢形成的因素众多,尿蛋白阳性和低龄是双J管表面结石形成的重要危险因素。
[Abstract]:Objective to understand the formation of double J tube wall stones and analyze the influencing factors of double J tube wall stone formation. Methods A total of 84 patients with upper urinary calculi underwent ureteroscopy combined with holmium laser lithotripsy from February to July 2014 were included. The clinical data were collected and the formation of double J tube wall stones was observed by computer microscope. T test and 蠂 2 test were used to analyze the relationship between the clinical data and the formation of wall stones. The Fisher exact probability method was used to analyze the relationship between the clinical data and the formation of wall stones. Results the mean indwelling time of double J tube was 17.0 卤6.0 days and 67 cases (79.8%) of double J tube formed wall stone membrane. The stone membrane forming group was younger than the unformed stone membrane group (44.9 卤11.5) years old vs.(54.4 卤12.6years old, the uroprotein positive group had a higher formation rate of the wall stone membrane (P 0.004), and the formation rate of the stone membrane was higher than that of the patients with positive urinary tract infection (2628% 92.9% vs 41% 56 / 73.2P 0.035); the patients with positive urinary tract infection had higher formation rate of stone membrane than those with negative stone membrane formation group (P 0.002), and the patients with positive urinary tract infection had higher stone membrane formation rate than those with positive urinary tract infection (P 0.002), and those with positive urinary tract infection had higher stone membrane formation rate than those with positive urinary tract infection (vs.(54.4 卤12.6) years old. The rate of formation of stone membrane in hematuria positive group was higher than that in negative group. The rate of formation of stone membrane was 67 / 80 / 83.8 / 0 / 0 / 4 / 0 / 0. 001g. Different sex, double J tube retention time, serum calcium, inorganic phosphorus, uric acid, urine pH, stone formation rate between the type of stone there was no significant difference (P 0.05). Five cases of double J tube wall stones were analyzed for stone composition. The results of logistic regression showed that the formation of stone membrane was associated with low age and urine protein (P0.05), but not with hematuria and urinary tract infection (P0.05). Conclusion there are many factors influencing the formation of wall stone. Urine protein positive and young age are important risk factors for the formation of double J tube surface stones.
【作者单位】：四川大学华西医院泌尿外科;
【基金】：教育部博士点基金(No.20110181130003) 四川大学交叉学科研究项目(No.2010SCU22002) 成都市科技攻关项目(No.10GGYB749SW-023) 四川省科技厅科技支撑计划项目(No.2014SZ0028)资助
【分类号】：R699

【共引文献】