尿路感染患者病原菌分布及耐药性分析

发布时间：2018-05-19 23:41

本文选题：尿路感染 + 病原菌　；参考：《中华实用诊断与治疗杂志》2014年01期

【摘要】：目的分析尿路感染患者病原菌的临床分布特征及耐药性,为临床治疗提供依据。方法对1 180份临床送检无菌中段尿标本进行病原菌培养及药物敏感试验,分析病原菌临床分布特征及耐药情况。结果 1 180份标本共培养出病原菌356株,其中革兰阴性菌265株,革兰阳性菌69株,真菌22株。检出率居前5位的病原菌分别是大肠埃希菌173株,表皮葡萄球菌30株,奇异变形杆菌28株,肺炎克雷伯菌20株,铜绿假单胞菌20株。药物敏感试验结果显示革兰阴性菌对青霉素类、头孢类、喹诺酮类等抗生素耐药率均较高,革兰阳性菌对青霉素类耐药率高达80%以上,未出现耐万古霉素及替考拉宁的葡萄球菌和肠球菌。结论尿路感染病原菌耐药率不断增高,应及时行细菌鉴定及药物敏感试验,并根据药物敏感试验结果合理用药。
[Abstract]:Objective to analyze the clinical distribution and drug resistance of pathogenic bacteria in patients with urinary tract infection. Methods the pathogenic bacteria culture and drug sensitivity test were carried out in 1 180 samples of aseptic urine, and the clinical distribution characteristics and drug resistance of pathogens were analyzed. Results 356 strains of pathogenic bacteria were cultured in 1 180 specimens, of which 265 were Gram-negative bacteria, 69 Gram-positive bacteria and 22 fungi. The top 5 pathogens were Escherichia coli 173 strains, Staphylococcus epidermidis 30 strains, Proteus mirabilis 28 strains, Klebsiella pneumoniae 20 strains, Pseudomonas aeruginosa 20 strains. The results of drug sensitivity test showed that Gram-negative bacteria had higher resistance to penicillin, cephalosporins and quinolones, and Gram-positive bacteria were more than 80% resistant to penicillin. No vancomycin and teicoplanin resistant staphylococci and enterococci were found. Conclusion the rate of drug resistance of pathogenic bacteria in urinary tract infection is increasing constantly. The bacteria identification and drug sensitivity test should be carried out in time, and the rational use of drugs should be based on the results of drug sensitivity test.
【作者单位】：郑州大学人民医院;河南省人民医院检验科;
【分类号】：R446.5

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