经肾造瘘管注射血凝酶防治经皮肾术后出血的临床分析

发布时间：2018-05-21 09:39

本文选题：经皮肾 + 血凝酶　；参考：《中南大学》2014年硕士论文

【摘要】：目的：探讨经肾造瘘管注射血凝酶用于预防与治疗微创经皮肾(mPCNL)术后出血并发症的效果。方法：选取2013年6月到2014年1月间中南大学湘雅医院泌尿外科行mPCNL的226例病人。所有病例随机分为四组：6U血凝酶组、4U血凝酶组、生理盐水组和对照组。比较四组患者术后前3天出血量、术后发热率及并发症率。采用SPSS17.0统计软件包以方差分析(one-way ANOVA)对比四组间数据。结果：有226例患者纳入本实验,各组患者术前一般资料无统计学差异。术后前3天出血量方面,4U血凝酶组和6U血凝酶组的术后前三天出血量明显低于生理盐水组和对照组,差异具有统计学意义(P0.05)。4U血凝酶组和6U血凝酶组术后前三天出血量无明显差异(P0.05)。生理盐水组和对照组术后前三天出血量无明显差异(P0.05)。各组患者在术后发热率及并发症率方面无差异。结论：mPCNL术后由造瘘管注射血凝酶可以有效地减少术后出血,且该操作并不增加术后发热率及并发症率。
[Abstract]:Objective: to investigate the effect of hemagglutinin injection through renal fistula tube for the prevention and treatment of bleeding complications after minimally invasive percutaneous nephrostomy. Methods: 226 patients with mPCNL in Xiangya Hospital of Central South University from June 2013 to January 2014 were selected. All the patients were randomly divided into four groups: 1% 6 U hemocoagulase group, 4 U hemocoagulase group, normal saline group and control group. The bleeding volume, postoperative fever rate and complication rate were compared between the four groups. The four groups of data were compared with one-way ANOVA by SPSS17.0 software package. Results: 226 patients were included in this study. In the first 3 days after operation, the volume of blood loss in the 4U and 6U hemagglutinin groups was significantly lower than that in the saline group and the control group. There was no significant difference in the amount of blood loss between P0.05U group and 6U group in the first three days after operation. There was no significant difference in blood loss between the saline group and the control group on the first three days after operation. There was no difference in postoperative fever rate and complication rate in all groups. Conclusion injection of hemocoagulase into the fistula tube can effectively reduce postoperative bleeding and does not increase the rate of postoperative fever and complications.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R699

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