肾移植术后新发糖尿病:危险因素的回顾性分析

发布时间：2018-06-02 09:09

  本文选题：肾移植 + 糖尿病　； 参考：《中国组织工程研究》2017年20期

【摘要】：背景:肾移植后代谢紊乱对预后的影响,尤其是新发糖尿病开始引起学者的重视。目的:了解肾移植术后新发糖尿病的危险因素,为识别肾移植术后新发糖尿病的高危患者,以及采取相应的预防措施提供参考依据。方法:回顾性病例分析365例同种异体肾移植患者的临床资料,根据是否发生肾移植术后新发糖尿病,将患者分为肾移植术后新发糖尿病组(71例)和非肾移植术后新发糖尿病组(294例),采用单因素分析和非条件Logistic回归分析肾移植术后新发糖尿病的独立危险因素。结果与结论:(1)1年内肾移植术后新发糖尿病的累积发病率为19.45%;(2)非条件Logistic回归中分析结果显示,年龄≥45岁、体质量指数≥25 kg/m~2、糖尿病家族史、急性排斥反应是肾移植术后新发糖尿病发生的独立危险因素;(3)结果提示,移植时年龄、糖尿病家族史、移植前体质量指数较高及移植后急性排斥反应的发生将会增加肾移植术后新发糖尿病的风险。
[Abstract]:Background: metabolic disorders after renal transplantation have a significant impact on prognosis, especially new diabetes mellitus. Objective: to investigate the risk factors of new diabetes mellitus after renal transplantation, and to provide reference for identifying high risk patients with new diabetes mellitus after renal transplantation and taking corresponding preventive measures. Methods: the clinical data of 365 patients with renal allograft transplantation were analyzed retrospectively. The patients were divided into two groups: renal transplantation group (n = 71) and non-renal transplantation group (n = 294). Univariate analysis and unconditioned Logistic regression analysis were used to analyze the independent risk factors of new diabetes mellitus after renal transplantation. Results and conclusion within 1 year, the cumulative incidence of new diabetes mellitus after renal transplantation was 19.4545 / 2) the age 鈮，

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