良性前列腺增生症与心脑血管疾病危险因素关联性研究

发布时间：2018-06-03 02:24

  本文选题：前列腺增生症 + 高血压　； 参考：《广东医学》2017年08期

【摘要】：目的探讨心脑血管疾病危险因素高血压、糖尿病、肥胖、血脂异常与良性前列腺增生症(BPH)的关系。方法选取205例BPH患者的临床资料,然后分别按照是否合并高血压、糖尿病、肥胖、血脂异常分为BPH非高血压组(A1组,n=115)和BPH合并高血压组(A2组,n=90)、BPH非高血糖组(B1组,n=169)和BPH合并高血糖组(B2组,n=36)、BPH非肥胖组(C1组,n=142)和BPH合并肥胖组(C2组,n=63)、BPH非血脂异常组(D1组,n=151)和BPH合并血脂异常组(D2组,n=54),再分别进行两组间回顾性对比分析;最后进一步分析前列腺体积(PV)分别与收缩压(SBP)、舒张压(DBP)、空腹血糖(FBG)、糖化血红蛋白(HbA_(1C))、体质指数(BMI)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和血清前列腺特异性抗原(PSA)之间的相关性。结果 BPH分别合并高血压、糖尿病、肥胖患者与单纯性BPH患者相比,PV增大[(66.21±20.78)mL vs(56.79±29.31)mL、(68.98±27.67)mL vs(59.20±21.02)mL、(67.01±18.98)mL vs(58.45±23.64)mL],差异有统计学意义(P0.05);并且高血压分级与PV呈正相关(rs=0.321,P0.05);同样SBP、DBP、FBG、BMI、血清总PSA(t-PSA)和血清游离PSA(f-PSA)与PV呈正相关(r=0.229,P0.05;r=0.188,P0.05;r=0.180,P0.05;r=0.311,P0.05;r=0.161,P0.05;r=0.161,P0.05)。结论高血压、糖尿病、肥胖可能分别是促发BPH的危险因素,控制血压、血糖、体重可作为预防前列腺增生的手段之一。
[Abstract]:Objective to investigate the relationship between hypertension, diabetes, obesity, dyslipidemia and benign prostatic hyperplasia (BPH). Methods the clinical data of 205 patients with BPH were selected, and then according to whether the patients were complicated with hypertension, diabetes, obesity, Dyslipidemia was divided into two groups: BPH non-hypertension group (A-1), BPH with hypertension group A _ 2 (group A _ 2) and BPH with hyperglycemia group B _ 1 (group B _ 1) and BPH with hyperglycemia group B _ 2 (group B _ 2) and BPH group with obesity group C _ 2 group without hyperlipidemia group C _ 2 group with no hyperlipidemia group D _ 1). BPH combined with dyslipidemia group (D 2 group) and D 2 group (P < 0.05) were compared and analyzed retrospectively between the two groups. Finally, we further analyze the relationship between SBP, DBP, FBGG, HbA1C, BMI, TC, TG, HDL-C, LDL-C. The correlation between LDL-C and serum prostate specific antigen (PSA). Results BPH was associated with hypertension and diabetes respectively. 鑲ヨ儢鎮ｈ，

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