持续低效血液透析与连续性肾脏替代治疗感染性急性肾损伤的效果观察

发布时间：2018-06-07 15:49

  本文选题：急性肾损伤 + 连续性肾脏替代治疗　； 参考：《中国现代医学杂志》2015年36期

【摘要】：目的观察持续低效血液透析(SLED)与连续性肾脏替代治疗(CRRT)在感染性急性肾损伤(Septic AKI)患者的治疗效果。方法回顾性分析,病例收集为入住SICU资料完整的2012 KDIGO 2期Septic AKI患者57例,分为SLED组及CRRT组。比较各组患者治疗前及治疗后48 h的血清肌值酐、血尿素氮、血清钾、白介素-6、肿瘤坏死因子α、平均动脉压、氧合指数、血乳酸值、尿量、APACHEⅡ评分、SOFA评分;机械通气时间及住ICU时间;28及90 d的病死率。结果经过48 h的治疗,2组患者的血清肌酐值、血尿素氮、血清钾、平均动脉压、氧合指数、血清乳酸值、尿量、APACHEⅡ评分及SOFA评分均较治疗前明显好转,但治疗后两组患者的上述指标比较差异无统计学意义;2组患者的机械通气时间、住ICU时间、28及90 d病死率比较差异无统计学意义。结论 SLED及CRRT均是治疗Septic AKI患者的有效措施,一定程度上SLED可以替代CR R T成为治疗Septic AKI患者的有效方式。
[Abstract]:Objective to observe the effect of continuous low effective hemodialysis (SLED) and continuous renal replacement therapy (CRRT) on septic AKI patients with infectious acute renal injury. Methods retrospective analysis showed that 57 cases of stage 2 Septic AKI admitted to SICU were divided into SLED group and CRRT group. Serum creatinine, blood urea nitrogen, serum potassium, interleukin-6, tumor necrosis factor 伪, mean arterial pressure, oxygenation index, blood lactic acid and urine volume were compared before and 48 hours after treatment. The mortality of mechanical ventilation time and ICU stay was 28 and 90 days. Results the serum creatinine, blood urea nitrogen, serum potassium, mean arterial pressure, oxygenation index, serum lactate, urine volume Apache 鈪，

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