银屑病与勃起功能障碍相关性的meta分析

发布时间：2018-06-23 05:39

本文选题：银屑病 + 勃起功能障碍　；参考：《中华男科学杂志》2017年03期

【摘要】：目的:系统评价银屑病与勃起功能障碍(ED)的相关性。方法:计算机检索Cochrane Library、EM-base、Pub Med、OVID、Medline、维普、万方、中国知网(CNKI)、中国生物医学文献服务系统(Sino Med)数据库,搜索银屑病与ED相关的文献,检索时间为数据库建立至2016年6月。分别由两名研究人员按照纳入、排除标准提取相关数据,运用Review Manager 5.3软件对银屑病与ED的相关性,IIEF-5评分进行meta分析。结果:总共纳入6篇文献,采用固定效应模型分析,结果显示银屑病与ED[OR=1.92(95%CI 1.53~2.40)]具有相关性,差异具有统计学意义(P0.01);随机效应模型分析其中3篇的IIEF-5评分,结果显示银屑病患者IIEF-5评分[MD=-3.11(95%CI-4.85~-1.37)]显著低于非银屑病者,差异具有统计学意义(P0.01)。结论:银屑病与ED存在相关性,银屑病患者可能具有更高的ED发生率,但仍需要更高质量的文献证实。
[Abstract]:Objective: to evaluate the relationship between psoriasis and erectile dysfunction (Ed). Methods: the database of Cochrane Library EM-basePub MedOVIDCline, Weip, Wanfang, CNKI, China Biomedical document Service system (Sino Med) was searched by computer. The search time was up to June 2016. The data were extracted by two researchers according to the inclusion and exclusion criteria, and the correlation between psoriasis and Ed was analyzed by meta using Review Manager 5.3 software. Results: a total of 6 articles were included and analyzed by fixed effect model. The results showed that psoriasis was correlated with Ed [OR1.92 (95CI 1.532.40)], the difference was statistically significant (P0.01), and the IIEF-5 score of 3 articles were analyzed by random effect model. The results showed that the IIEF-5 score of psoriasis patients was significantly lower than that of non-psoriasis patients (P 0.01). Conclusion: psoriasis is associated with Ed. Psoriasis may have a higher incidence of Ed, but higher quality literature is needed.
【作者单位】：西南医科大学附属医院泌尿外科;
【基金】：四川省科技厅基金(14CJ0803)~~
【分类号】：R698.1;R758.63

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