时间-空间标记反转脉冲技术在肾脏皮髓质分离中的应用及时间参数优化

发布时间：2018-06-24 21:34

本文选题：肾皮质 + 肾髓质　；参考：《中国医学影像技术》2017年05期

【摘要】：目的探讨磁共振时间—空间双重标记反转脉冲(T-SLIP)技术在肾脏皮髓质分离中的应用及显示肾脏皮髓质分离最佳的黑血翻转时间(BBTI)。方法选择健康志愿者60名,采用结合T-SLIP脉冲的稳态自由进动序列(SSFP)行上腹部扫描。采用6个BBTI值(800、1 000、1 200、1 400、1 600、1 800ms)进行冠状位T-SLIP SSFP序列扫描。采用4分法分析图像质量,并通过图像训练算法自动分割肾脏皮髓质区域,分别计算皮髓质的信号强度(SI),获得不同BBTI值时肾脏皮髓质的相对信号强度比(SIR),获得最佳BBTI值。结果 BBTI值为1 200ms时,图像质量的评分最高。不同BBTI值时,SIR差异有统计学意义(P=0.013),当BBTI为1 200ms时,SIR值最大,肾皮髓质间SI对比最明显。结论 T-SLIP技术可在不使用对比剂的情况下清晰显示肾脏皮髓质,当BBTI值为1 200ms时皮髓质分离显示最好。
[Abstract]:Objective to investigate the application of magnetic resonance time-space double label reverse pulse (T-SLIP) technique in the separation of renal dermatomedullary and display the best black blood turnover time (BBTI) for renal dermatomedullary separation. Methods 60 healthy volunteers were scanned by steady-state free precession sequence (SSFP) combined with T-SLIP pulse. The coronal T-SLIP SSFP sequences were scanned with six BBTI values (800 ~ (1 000) ~ (1 000) ~ 1 400 ~ 1 600 ~ (-1) 800ms). The image quality was analyzed by 4-score method, and the image training algorithm was used to automatically segment the medullary area of the kidney. The signal intensity (SI) of the medulla was calculated respectively. The relative signal intensity ratio (Sir) of the renal medulla was obtained with different BBTI values, and the best BBTI value was obtained. Results when the BBTI value was 1 200ms, the image quality score was the highest. There was significant difference in Sir between different BBTI values (P0. 013). When BBTI was 1 200ms, Sir value was the highest and SI contrast between renal medulla was the most obvious. Conclusion T-SLIP technique can clearly display renal medulla without contrast medium, and the separation of renal medulla is the best when the BBTI value is 1 200ms.
【作者单位】：贵州医科大学医学影像学院;贵州医科大学附属肿瘤医院影像科;东芝医疗系统(中国)磁共振临床应用部;东芝医疗系统(中国)研发中心;
【分类号】：R445.2;R692

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