非嵌合型Klinefelter综合征患者显微取精术研究进展

发布时间：2018-06-26 18:24

  本文选题：Klinefelter综合征 + 非梗阻性无精子症　； 参考：《中华男科学杂志》2017年09期

【摘要】：Klinefelter综合征(KS)是男性最常见的性染色体异常疾病,第二性征发育迟滞或不发育及不育是其最常见临床表现。随着现代辅助生殖技术的发展,KS患者拥有自己遗传学意义后代成为可能。显微睾丸取精术(m TESE)是公认的最佳取精术式,本文就其预测指标、取精成功率、手术方法、术后并发症、术前性激素替代治疗及术后睾酮下降等问题进行综述。
[Abstract]:Klinefelter syndrome (KS) is the most common sex chromosome abnormality in males, and the second sexual sign is the most common clinical manifestation. With the development of modern assisted reproductive technology, it is possible for KS patients to have their own offspring with genetic significance. Microtesticular spermatoplasty (mTESE) is considered as the best method for spermaticotomy. This article reviews its prediction index, successful rate of spermatogenesis, operative methods, postoperative complications, preoperative hormone replacement therapy and postoperative testosterone decline.
【作者单位】： 华中科技大学同济医学院附属同济医院泌尿外科;华中科技大学同济医学院附属同济医院泌尿外科研究所;
【分类号】：R698.2
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本文编号：2070994