输尿管软镜与经皮肾镜治疗肾结石的相关研究

发布时间：2018-06-28 17:41

  本文选题：输尿管镜钬激光碎石术 + 经皮肾镜钬激光碎石术　； 参考：《中国现代医学杂志》2017年23期

【摘要】：目的探讨输尿管镜与经皮肾镜对术后肾功能、凝血功能及氧化应激产物的影响。方法选取该院收治的肾结石患者52例,随机分为经皮肾镜组和输尿管镜组,每组各26例,经皮肾镜组给予经皮肾镜钬激光碎石术治疗,输尿管镜组给予输尿管镜钬激光碎石术治疗,术后对患者的肾功能、凝血功能、氧化应激产物及治疗效果进行检测。结果术后输尿管镜组与经皮肾镜组比较:(1)输尿管镜组血清Scr、NGAL、Cys C和MDA水平较低,血清R、K和GSH-Px水平较高,α、MA水平较低;(2)输尿管镜组的术中出血量较低,清石率较高。结论与经皮肾镜比较,输尿管镜对肾结石患者肾功能、凝血功能的影响更小,氧化应激反应较轻,术中出血量较低,清石率较高,对临床有指导意义。
[Abstract]:Objective to investigate the effects of ureteroscopy and percutaneous nephroscopy on renal function, coagulation and oxidative stress products. Methods Fifty-two patients with renal calculi were randomly divided into percutaneous nephroscope group and ureteroscopic group, each group with 26 cases. Percutaneous nephroscope holmium laser lithotripsy was performed in each group. Ureteroscope group was treated with ureteroscopic holmium: YAG laser lithotripsy. Renal function, coagulation function, oxidative stress product and therapeutic effect were measured after operation. Results the results showed that: (1) the levels of serum Scrn NGALCys C and MDA in ureteroscopy group were lower than those in percutaneous nephroscopy group, the levels of serum RK and GSH-Px were higher, and the level of 伪 -TMA was lower in ureteroscopy group, (2) the amount of intraoperative bleeding was lower and the stone clearing rate was higher in ureteroscopy group. Conclusion compared with percutaneous nephroscopy, ureteroscopy has less effect on renal function and coagulation function, less oxidative stress, lower blood loss during operation and higher stone clearance rate, which is of guiding significance to clinical practice.
【作者单位】： 贵州省镇远人民医院;
【基金】：贵州省科学技术进步项目(No:2011J_038)
【分类号】：R699.2
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