尿肠球菌尿路感染流行病学及临床特征分析

发布时间：2018-06-29 04:02

  本文选题：尿路感染 + 尿肠球菌　； 参考：《中国病原生物学杂志》2017年10期

【摘要】：目的研究尿路感染患者携带尿肠球菌流行病学及临床特征,为尿路感染的诊治提供指导。方法收集206例尿路感染患者临床送检尿液标本,分离尿肠球菌,同一患者剔除重复株。采用VITEK32细菌检测分析仪检测菌落,并采用API板条鉴定菌种。药敏试验采用K-B法,结果判定参照CLSI2016版。采用SPSS20.0软件对数据进行统计学分析。结果检出49例尿肠球菌感染者,≤44岁感染者12例,感染率18.46%;45~岁感染者17例,感染率24.64%;≥60岁感染者20例,感染率27.78%。≤44岁和44岁患者感染率差异无统计学意义(χ2=1.4853,P0.05);60岁和≥60岁患者感染率差异有统计学意义(χ2=0.9727,P0.05)。男性患者19例,感染率17.12%(19/111);女性患者30例,感染率31.58%(30/95);男、女患者感染率差异无统计学意义(χ2=5.9056,P0.05)。临床表现以怕冷、发热、腰痛等全身症状为主,且无症状性菌尿、尿路刺激、全身症状的患者分别有14、9和22例,感染率28.57%、18.37%和44.90%。实验室检查中,白细胞、血沉、C反应蛋白、降钙素原、IgG、C3、肌酐值、胱蛋白酶抑制剂C、N-乙酰-β-D氨基葡萄糖苷酶、β2-微球蛋白、微量白蛋白以及内毒素异常患者分别为24、9、8、3、7、8、7、8、28、22、29和20例,分别占48.97%、18.37%、16.33%、6.12%、14.29%、16.33%、14.29%、16.33%、57.14%、44.90%、59.18%和40.82%。49株尿肠球菌对诺氟沙星、庆大霉素、利福平、利奈唑胺、万古霉素、替考拉宁的耐药率分别为61.22%、48.98%、32.65%、16.33%、0.00%和0.00%。结论尿肠球菌尿路感染以老年患者常见,女性患者高发,临床表现以全身症状为主,实验室检查以微量白蛋白和白细胞指标异常为主要特征。尿肠球菌尿路感染治疗可合理使用万古霉素和替考拉宁。
[Abstract]:Objective to study the epidemiology and clinical characteristics of enterococci carrying urinary tract infection in order to provide guidance for the diagnosis and treatment of urinary tract infection. Methods urine samples from 206 patients with urinary tract infection were collected and Enterococci were isolated and repeated strains were removed from the same patient. The colony was detected by VITEK32 bacterial analyzer, and the bacteria species were identified by API strip. The drug sensitivity test was performed by K-B method and the results were determined by CLSI2016. SPSS 20.0 software was used to analyze the data. Results there were 49 cases of enterococcus infection in urine, 12 cases of infection 鈮，

本文编号：2080767