高危非肌层浸润性膀胱癌的治疗进展
发布时间：2018-08-04 07:54
【摘要】：膀胱癌是泌尿系统常见恶性肿瘤,高危非肌层浸润性膀胱癌(NMIBC)的治疗是目前临床中的主要难点之一,早期诊断、个体化治疗并加强随访对改善患者预后具有十分重要的意义。手术配合辅助性膀胱灌注治疗是治疗高危NMIBC的首选方案,手术治疗包括经尿道膀胱肿瘤电切术(TURBT)、经尿道激光手术、Ⅱ期根治性膀胱切除术、光动力学辅助TURBT和荧光膀胱镜辅助TURBT等;辅助性膀胱灌注治疗包括膀胱灌注免疫治疗和膀胱灌注化疗,术后膀胱灌注化疗和免疫治疗有利于改善高危NMIBC患者的预后水平,但在灌注治疗中对于药物、时机、疗程、剂量的选择目前尚存争议。近年来,随着精准医疗和转化医学的发展,又涌现了基因治疗、靶向治疗等精准治疗手段。
[Abstract]:Bladder cancer is a common malignant tumor of urinary system. The treatment of high risk non-myometrial invasive bladder cancer (NMIBC) is one of the main difficulties in clinical practice. Early diagnosis, individualized treatment and enhanced follow-up are of great significance to improve the prognosis of patients. Surgery combined with adjuvant bladder perfusion therapy is the first choice in the treatment of high risk NMIBC. The surgical treatment includes transurethral resection of bladder tumor by (TURBT), transurethral laser surgery and stage 鈪，
本文编号：2163161
[Abstract]:Bladder cancer is a common malignant tumor of urinary system. The treatment of high risk non-myometrial invasive bladder cancer (NMIBC) is one of the main difficulties in clinical practice. Early diagnosis, individualized treatment and enhanced follow-up are of great significance to improve the prognosis of patients. Surgery combined with adjuvant bladder perfusion therapy is the first choice in the treatment of high risk NMIBC. The surgical treatment includes transurethral resection of bladder tumor by (TURBT), transurethral laser surgery and stage 鈪，
本文编号：2163161
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